Exposure Profile to Traffic Related Pollution in Pediatric Age: A Biomonitoring Study

Arianna Antonucci, Carmela Protano, Maria Luisa Astolfi, Vincenzo Mattei, Francesca Santilli, Stefano Martellucci and Matteo Vitali
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Arianna Antonucci: Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, 00185 Rome, Italy
Carmela Protano: Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, 00185 Rome, Italy
Maria Luisa Astolfi: Department of Chemistry, “Sapienza” University of Rome, 00185 Rome, Italy
Vincenzo Mattei: Biomedicine and Advanced Technologies Rieti Center, Sabina Universitas, 02100 Rieti, Italy
Francesca Santilli: Biomedicine and Advanced Technologies Rieti Center, Sabina Universitas, 02100 Rieti, Italy
Stefano Martellucci: Biomedicine and Advanced Technologies Rieti Center, Sabina Universitas, 02100 Rieti, Italy
Matteo Vitali: Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, 00185 Rome, Italy

IJERPH, 2021, vol. 18, issue 19, 1-12

Abstract: The aim of this study was to trace an exposure profile to traffic-derived pollution during pediatric age. For this purpose, two biomonitoring campaigns for the determination of urinary (u-) methyl tert-butyl ether (MTBE), ethyl tert-butyl ether (ETBE), tert-amyl methyl ether (TAME), and diisopropyl ether (DIPE) were carried out in two different periods of the year (summer 2017 and winter 2018), among a large sample of healthy children ( n = 736; 5–11 years old) living in rural and urban areas in central Italy. The quantification of u-MTBE, u-ETBE, u-TAME, and u-DIPE was performed by HS-SPME-GC/MS technique and information on participants was collected by a questionnaire. u-DIPE concentrations resulted always under the LOQ. u-TAME mean levels were similar in both seasons (18.7 ng L ?1 in summer vs. 18.9 ng L ?1 in winter), while u-MTBE and u-ETBE levels were, respectively, 69.9 and 423.5 ng L ?1 (summer) and 53.3 and 66.2 ng L ?1 (winter). Main predictors of urinary excretion resulted the time spent in motor vehicles, being male and younger.

Keywords: pediatric age; traffic related pollution; human biomonitoring; methyl tert-butyl ether; ethyl tert-butyl ether; tert-amyl methyl ether; diisopropyl ether; urinary biomarkers (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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