Optimizing Operating Parameters of Electric Ultra-Low Volume Sprayer with Slightly Acidic Electrolyzed Solution for Efficient Virucidal Activity on Environmental Surfaces

Hae-Won Lee, So-Ra Yoon, Hyeyeon Song, Boyeon Park and Ji-Hyoung Ha
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Hae-Won Lee: Hygienic Safety and Analysis Center, World Institute of Kimchi, Gwangju 61755, Korea
So-Ra Yoon: Hygienic Safety and Analysis Center, World Institute of Kimchi, Gwangju 61755, Korea
Hyeyeon Song: Hygienic Safety and Analysis Center, World Institute of Kimchi, Gwangju 61755, Korea
Boyeon Park: Hygienic Safety and Analysis Center, World Institute of Kimchi, Gwangju 61755, Korea
Ji-Hyoung Ha: Hygienic Safety and Analysis Center, World Institute of Kimchi, Gwangju 61755, Korea

IJERPH, 2021, vol. 18, issue 19, 1-17

Abstract: Recently, and considering the COVID-19 pandemic, there has been a growing consensus that the disinfection of surfaces contaminated with pathogenic viral particles is essential. Chemical disinfectant sprays are effective at preventing the spread of infectious human noroviruses (Hu-NoVs) in healthcare and public areas. We assessed the virucidal activity of slightly acidic electrolyzed water (SAEW) spray on fomite surfaces. A multivariate statistical assessment that combined a response surface methodology (RSM) and a Box–Behnken design (BBD) was performed to define the optimal parameters of, and correlations among, experimental conditions. Spraying SAEW disinfectant (oxidation-reduction potential: 1123 mV, pH range: 5.12, available chlorine concentration: 33.22 ppm) resulted in the successful decontamination of Hu-NoV, with a 4-log reduction in viral particles on polyvinyl chloride, stainless steel, ceramic tile, and glass surfaces. Our experimental data revealed optimized treatment conditions for decontaminating Hu-NoV GI.6 and GII.4, using the numerical multiple optimized method (spraying rate: 218 mL/min, spraying time: 4.9 s, spraying distance: 0.9 m). These findings offer significant insights for designing optimal strategic control practices to prevent infectious disease, particularly Hu-NoV, transmission.

Keywords: human norovirus; optimization; response surface methodology; slightly acidic electrolyzed water; spray disinfection (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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