Association of Pesticides and Kidney Function among Adults in the US Population 2001–2010

En-Tzu Wan, Darsy Darssan, Shamshad Karatela, Simon A. Reid and Nicholas John Osborne
Additional contact information
En-Tzu Wan: School of Public Health, The University of Queensland, Brisbane 4006, Australia
Darsy Darssan: School of Public Health, The University of Queensland, Brisbane 4006, Australia
Shamshad Karatela: School of Public Health, The University of Queensland, Brisbane 4006, Australia
Simon A. Reid: School of Public Health, The University of Queensland, Brisbane 4006, Australia
Nicholas John Osborne: School of Public Health, The University of Queensland, Brisbane 4006, Australia

IJERPH, 2021, vol. 18, issue 19, 1-9

Abstract: Chronic kidney disease of unknown cause is prevalent in a range of communities; however, its etiology remains unclear. We examined the association between pesticide exposures and the risk of kidney function loss using four waves of the National Health and Nutrition Examination Survey (NHANES) to identify a pathological pathway. We pooled data from four cross-sectional waves of NHANES, with 41,847 participants in total. Exposure to malathion increased the risk of low kidney function (aOR = 1.26, 95% CI = 1.01–1.56) in the adjusted model. Increased risk of low kidney function was not found among those exposed to 2,4-D (aOR = 0.88, 95% CI = 0.72–1.09), 3,5,6-trichloropyridinol (aOR = 0.96, 95% CI = 0.83–1.12), and 3-PBA (aOR = 1.03, 95% CI = 0.94–1.13). Our findings provide evidence of altered kidney function in people exposed to malathion, highlighting the potential of organophosphate pesticides’ role in renal injury.

Keywords: pesticides; organophosphate insecticide; malathion; kidney function; NHANES (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/18/19/10249/pdf (application/pdf)
https://www.mdpi.com/1660-4601/18/19/10249/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:18:y:2021:i:19:p:10249-:d:646138

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().