Environmental and Occupational Short-Term Exposure to Airborne Particles and FEV 1 and FVC in Healthy Adults: A Systematic Review and Meta-Analysis

Alan da Silveira Fleck, Margaux L. Sadoine, Stéphane Buteau, Eva Suarthana, Maximilien Debia and Audrey Smargiassi
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Alan da Silveira Fleck: Department of Environmental and Occupational Health, School of Public Health, University of Montreal, 2375 Chem. de la Côte-Sainte-Catherine, Montreal, QC H3T 1A8, Canada
Margaux L. Sadoine: Department of Environmental and Occupational Health, School of Public Health, University of Montreal, 2375 Chem. de la Côte-Sainte-Catherine, Montreal, QC H3T 1A8, Canada
Stéphane Buteau: Institut National de Sante Publique du Québec (INSPQ), 190 Boul Crémazie E, Montreal, QC H2P 1E2, Canada
Eva Suarthana: Research Institute of the McGill University Health Center, 2155 Rue Guy, Montreal, QC H3H 2L9, Canada
Maximilien Debia: Department of Environmental and Occupational Health, School of Public Health, University of Montreal, 2375 Chem. de la Côte-Sainte-Catherine, Montreal, QC H3T 1A8, Canada
Audrey Smargiassi: Department of Environmental and Occupational Health, School of Public Health, University of Montreal, 2375 Chem. de la Côte-Sainte-Catherine, Montreal, QC H3T 1A8, Canada

IJERPH, 2021, vol. 18, issue 20, 1-19

Abstract: Background: No study has compared the respiratory effects of environmental and occupational particulate exposure in healthy adults. Methods: We estimated, by a systematic review and meta-analysis, the associations between short term exposures to fine particles (PM 2.5 and PM 4 ) and certain parameters of lung function (FEV 1 and FVC) in healthy adults. Results: In total, 33 and 14 studies were included in the qualitative synthesis and meta-analyses, respectively. In environmental studies, a 10 µg/m 3 increase in PM 2.5 was associated with an FEV 1 reduction of 7.63 mL (95% CI: ?10.62 to ?4.63 mL). In occupational studies, an increase of 10 µg/m 3 in PM 4 was associated with an FEV 1 reduction of 0.87 mL (95% CI: ?1.36 to ?0.37 mL). Similar results were observed with FVC. Conclusions: Both occupational and environmental short-term exposures to fine particles are associated with reductions in FEV 1 and FVC in healthy adults.

Keywords: particulate matter; lung function; healthy adults; short-term; occupational exposures; environmental exposures (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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