Acceptability of Clinical Trials on COVID-19 during Pregnancy among Pregnant Women and Healthcare Providers: A Qualitative Study

Elena Marbán-Castro, Clara Pons-Duran, Laura García-Otero, Haily Chen, Luis Bernardo Herrera, María del Mar Gil, Anna Goncé, Elena Ferriols-Pérez, Miguel Ángel Rodríguez, Paloma Toro, Azucena Bardají, Raquel González, Clara Menéndez and Cristina Enguita-Fernàndez
Additional contact information
Elena Marbán-Castro: ISGlobal, Hospital Clínic-Universitat de Barcelona, 08036 Barcelona, Spain
Clara Pons-Duran: ISGlobal, Hospital Clínic-Universitat de Barcelona, 08036 Barcelona, Spain
Laura García-Otero: ISGlobal, Hospital Clínic-Universitat de Barcelona, 08036 Barcelona, Spain
Haily Chen: ISGlobal, Hospital Clínic-Universitat de Barcelona, 08036 Barcelona, Spain
Luis Bernardo Herrera: ISGlobal, Hospital Clínic-Universitat de Barcelona, 08036 Barcelona, Spain
María del Mar Gil: Obstetrics and Gynecology Department, Hospital Universitario de Torrejón, Torrejón de Ardoz, 28850 Madrid, Spain
Anna Goncé: Fetal Medicine Research Center, BCNatal—Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic and Hospital Sant Joan de Déu) and Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
Elena Ferriols-Pérez: Department Gynaecology and Obstetrics, Parc de Salut Mar University Hospital, 08003 Barcelona, Spain
Miguel Ángel Rodríguez: HM Puerta del Sur, Móstoles, 28938 Madrid, Spain
Paloma Toro: Obstetrics and Gynecology Department, Complejo Asistencial de Segovia, Hospital General de Segovia, 40002 Segovia, Spain
Azucena Bardají: ISGlobal, Hospital Clínic-Universitat de Barcelona, 08036 Barcelona, Spain
Raquel González: ISGlobal, Hospital Clínic-Universitat de Barcelona, 08036 Barcelona, Spain
Clara Menéndez: ISGlobal, Hospital Clínic-Universitat de Barcelona, 08036 Barcelona, Spain
Cristina Enguita-Fernàndez: ISGlobal, Hospital Clínic-Universitat de Barcelona, 08036 Barcelona, Spain

IJERPH, 2021, vol. 18, issue 20, 1-14

Abstract: Participation of pregnant women in clinical trials entails challenges mainly related to concerns about the risks for fetuses. We undertook a qualitative study from June to October 2020 to assess the acceptability of participating in COVID-19 clinical trials among pregnant women in Spain. Phenomenology and grounded theory were used as methodological approaches. Semi-structured interviews were conducted with 24 pregnant women and six healthcare providers. Women were unsure if pregnancy was a risk factor to acquire the infection or to develop severe disease and expressed the limited information they had received, which led to uncertainties and emotional suffering. They had concerns regarding participation in clinical trials on COVID-19, regardless of the drug under study. Healthcare providers alluded to the importance of involving pregnant women’s relatives at the recruitment visit of the clinical trial. These findings may be useful to facilitate pregnant women’s participation in clinical trials.

Keywords: COVID-19; pregnancy; acceptability; clinical trial; perceptions; healthcare professionals (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/18/20/10717/pdf (application/pdf)
https://www.mdpi.com/1660-4601/18/20/10717/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:18:y:2021:i:20:p:10717-:d:654914

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().