Trends of Hospital Admissions Due to Congenital Anomalies in England and Wales between 1999 and 2019: An Ecological Study

Abeer F. R. Alanazi, Abdallah Y. Naser, Prisca Pakan, Atheer F. Alanazi, Alyamama Abdulaziz A. Alanazi, Zahra Khalil Alsairafi and Fatemah M. Alsaleh
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Abeer F. R. Alanazi: Department of Pharmaceutical and Biological Sciences, UCL School of Pharmacy, London WC1E 6BT, UK
Abdallah Y. Naser: Department of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman 11622, Jordan
Prisca Pakan: Department of Microbiology, Medical Faculty, University of Nusa Cendana, Kupang 09200, Indonesia
Atheer F. Alanazi: Department of Biology, Ministry of Health, Riyadh 11176, Saudi Arabia
Alyamama Abdulaziz A. Alanazi: Department of Biological Sciences, School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK
Zahra Khalil Alsairafi: Department of Pharmacy Practice, Kuwait University, Kuwait City 12037, Kuwait
Fatemah M. Alsaleh: Department of Pharmacy Practice, Kuwait University, Kuwait City 12037, Kuwait

IJERPH, 2021, vol. 18, issue 22, 1-21

Abstract: Objectives : To investigate the trends in congenital anomalies-related hospital admissions in England and Wales. Methods : This was an ecological study that was conducted using hospital admission data taken from the Hospital Episode Statistics database in England and the Patient Episode Database for Wales. Congenital malformations, deformations and chromosomal abnormalities hospital admissions data were extracted for the period between April 1999 and March 2019. Results : Hospital admission rate increased by 4.9% [from 198.74 (95% CI 197.53–199.94) in 1999 to 208.55 (95% CI 207.39–209.71) in 2019 per 100,000 persons, trend test, p < 0.01]. The most common hospital admissions causes were congenital malformations of the circulatory system, the musculoskeletal system, genital organs, and the digestive system. The most notable increase in hospital admissions rate was observed in congenital malformations of the respiratory system (1.01-fold). The age group below 15 years accounted for 75.1% of the total number of hospital admissions. Males contributed to 57.5% of the whole number of hospital admission. Hospital admission rate between females was increased by 6.4% [from 162.63 (95% CI 161.10–164.16) in 1999 to 173.05 (95% CI 171.57–174.54) in 2019 per 100,000 persons]. Hospital admission rate between males was increased by 3.4% [from 236.61 (95% CI 234.72–238.50) in 1999 to 244.70 (95% CI 242.92–246.49) in 2019 per 100,000 persons]. Conclusions : Males had a higher percentage of hospitalisation compared to females. Further studies to investigate the factors associated with higher hospitalisation rate among males are needed.

Keywords: England; hospitalisation; congenital; United Kingdom; Wales (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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