Italian Children Exposure to Bisphenol A: Biomonitoring Data from the LIFE PERSUADED Project

Sabrina Tait, Fabrizia Carli, Luca Busani, Demetrio Ciociaro, Veronica Della Latta, Annalisa Deodati, Enrica Fabbrizi, Anna Paola Pala, Francesca Maranghi, Roberta Tassinari, Giacomo Toffol, Stefano Cianfarani, Amalia Gastaldelli, Cinzia La Rocca and PERSUADED Project Group Life
Additional contact information
Sabrina Tait: Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy
Fabrizia Carli: National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy
Luca Busani: Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy
Demetrio Ciociaro: National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy
Veronica Della Latta: National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy
Annalisa Deodati: Dipartimento Pediatrico, Universitario Ospedaliero “Bambino Gesù” Children’s Hospital, Piazza di Sant’Onofrio, 4, 00165 Rome, Italy
Enrica Fabbrizi: Unità Operativa Complessa Pediatria e Neonatologia, Ospedale Civile Augusto Murri, Via Augusto Murri, 21, 63900 Fermo, Italy
Anna Paola Pala: National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy
Francesca Maranghi: Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy
Roberta Tassinari: Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy
Giacomo Toffol: Associazione Culturale Pediatri, Via Montiferru, 6, 09070 Narbolia, Italy
Stefano Cianfarani: Dipartimento Pediatrico, Universitario Ospedaliero “Bambino Gesù” Children’s Hospital, Piazza di Sant’Onofrio, 4, 00165 Rome, Italy
Amalia Gastaldelli: National Research Council, Institute of Clinical Physiology, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy
Cinzia La Rocca: Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy
PERSUADED Project Group Life: Membership of the LIFE PERSUADED Project Group is provided in the Acknowledgments.

IJERPH, 2021, vol. 18, issue 22, 1-15

Abstract: A human biomonitoring (HBM) study on bisphenol A (BPA) in Italian children and adolescents was performed within the LIFE PERSUADED project, considering the residing areas, sex and age. The median urinary BPA level was 7.02 µg/L, with children living in the South of Italy or in urban areas having higher levels than those residing in the North or in rural areas. Children aged 4–6 years had higher BPA levels than those aged 7–10 and 11–14 years, but no differences were detected between sexes. The exposure in Italian children was higher compared to children from other countries, but lower than the HBM guidance value (135 µg/L). The estimated daily intake was 0.17 ?g/kg body weight (bw) per day, about 24-fold below the temporary Tolerable Daily Intake of 4 ?g/kg bw per day established by the European Food Safety Authority. However, this threshold was exceeded in 1.44% of the enrolled children, raising concern about the overall exposure of Italian young population.

Keywords: Bisphenol A; endocrine disruptor; children exposure; geographical areas; age; human biomonitoring (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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