Economic Evaluation of Community Tuberculosis Active Case-Finding Approaches in Cambodia: A Quasi-Experimental Study

Alvin Kuo Jing Teo, Kiesha Prem, Yi Wang, Tripti Pande, Marina Smelyanskaya, Lisanne Gerstel, Monyrath Chry, Sovannary Tuot and Siyan Yi
Additional contact information
Alvin Kuo Jing Teo: Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore 117549, Singapore
Kiesha Prem: Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore 117549, Singapore
Yi Wang: Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore 117549, Singapore
Tripti Pande: McGill International TB Centre, Montreal, QC H4A 3S5, Canada
Marina Smelyanskaya: Stop TB Partnership, 1218 Geneva, Switzerland
Lisanne Gerstel: KIT Royal Tropical Institute, 1092 AD Amsterdam, The Netherlands
Monyrath Chry: Cambodia Anti-Tuberculosis Association, Phnom Penh 12303, Cambodia
Sovannary Tuot: KHANA Centre for Population Health Research, Phnom Penh 12301, Cambodia
Siyan Yi: Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore 117549, Singapore

IJERPH, 2021, vol. 18, issue 23, 1-16

Abstract: This study aimed to estimate the costs and incremental cost-effectiveness of two community-based tuberculosis (TB) active case-finding (ACF) strategies in Cambodia. We also assessed the number needed to screen and test to find one TB case. Program and national TB notification data from a quasi-experimental study of a cohort of people with TB in 12 intervention operational districts (ODs) and 12 control ODs between November 2018 and December 2019 were analyzed. Two ACF interventions (ACF seed-and-recruit (ACF SAR) model and one-off roving (one-off) ACF) were implemented concurrently. The matched control sites included PCF only. We estimated costs using the program and published data in Cambodia. The primary outcome was disability-adjusted life years (DALY) averted over 14 months. We considered the gross domestic product per capita of Cambodia in 2018 as the cost-effectiveness threshold. ACF SAR needed to test 7.7 people with presumptive TB to identify one all-forms TB, while one-off ACF needed to test 22.4. The costs to diagnose one all-forms TB were USD 458 (ACF SAR) and USD 191 (one-off ACF). The incremental cost per DALY averted was USD 257 for ACF SAR and USD 204 for one-off ACF. Community-based ACF interventions that targeted key populations for TB in Cambodia were highly cost-effective.

Keywords: tuberculosis; active case finding; passive case finding; Cambodia; cost-effectiveness; disability-adjusted life years (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/18/23/12690/pdf (application/pdf)
https://www.mdpi.com/1660-4601/18/23/12690/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:18:y:2021:i:23:p:12690-:d:693165

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().