Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study

Franziska Dinah Welzel, Melanie Luppa, Alexander Pabst, Michael Pentzek, Angela Fuchs, Dagmar Weeg, Horst Bickel, Siegfried Weyerer, Jochen Werle, Birgitt Wiese, Anke Oey, Christian Brettschneider, Hans-Helmut König, Kathrin Heser, Hendrik van den Bussche, Marion Eisele, Wolfgang Maier, Martin Scherer, Michael Wagner and Steffi G. Riedel-Heller
Additional contact information
Franziska Dinah Welzel: Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103 Leipzig, Germany
Melanie Luppa: Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103 Leipzig, Germany
Alexander Pabst: Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103 Leipzig, Germany
Michael Pentzek: Institute of General Practice, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany
Angela Fuchs: Institute of General Practice, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany
Dagmar Weeg: Department of Psychiatry, Technical University of Munich, 81675 Munich, Germany
Horst Bickel: Department of Psychiatry, Technical University of Munich, 81675 Munich, Germany
Siegfried Weyerer: Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
Jochen Werle: Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany
Birgitt Wiese: Institute for General Practice, Hannover Medical School, 30625 Hannover, Germany
Anke Oey: Institute for General Practice, Hannover Medical School, 30625 Hannover, Germany
Christian Brettschneider: Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany
Hans-Helmut König: Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany
Kathrin Heser: Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, 53127 Bonn, Germany
Hendrik van den Bussche: Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany
Marion Eisele: Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany
Wolfgang Maier: Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, 53127 Bonn, Germany
Martin Scherer: Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany
Michael Wagner: Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, 53127 Bonn, Germany
Steffi G. Riedel-Heller: Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103 Leipzig, Germany

IJERPH, 2021, vol. 18, issue 23, 1-16

Abstract: Research on anxiety in oldest-old individuals is scarce. Specifically, incidence studies based on large community samples are lacking. The objective of this study is to assess age- and gender-specific incidence rates in a large sample of oldest-old individuals and to identify potential risk factors. The study included data from N = 702 adults aged 81 to 97 years. Anxiety symptoms were identified using the short form of the Geriatric Anxiety Inventory (GAI-SF). Associations of potential risk factors with anxiety incidence were analyzed using Cox proportional hazard models. Out of the N = 702 older adults, N = 77 individuals developed anxiety symptoms during the follow-up period. The incidence rate was 51.3 (95% CI: 41.2–64.1) per 1000 person-years in the overall sample, compared to 58.5 (95% CI: 43.2–72.4) in women and 37.3 (95% CI: 23.6–58.3) in men. Multivariable analysis showed an association of subjective memory complaints (HR: 2.03, 95% CI: 1.16–3.57) and depressive symptoms (HR: 3.20, 95% CI: 1.46–7.01) with incident anxiety in the follow-up. Incident anxiety is highly common in late life. Depressive symptoms and subjective memory complaints are major risk factors of new episodes. Incident anxiety appears to be a response to subjective memory complaints independent of depressive symptoms.

Keywords: incidence; anxiety; late life; cohort study (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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