Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland

Andrzej Prystupa, Jarosław Sak, Paweł Kiciński, Agnieszka Stenzel-Bembenek and Anna Błażewicz
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Andrzej Prystupa: Department of Internal Medicine, Medical University of Lublin, 20-081 Lublin, Poland
Jarosław Sak: Chair and Department of Humanities and Social Medicine, Medical University of Lublin, 20-093 Lublin, Poland
Paweł Kiciński: Department of Experimental Hematooncology, Medical University of Lublin, 20-093 Lublin, Poland
Agnieszka Stenzel-Bembenek: Chair and Department of Biochemistry and Molecular Biology, Medical University of Lublin, 20-093 Lublin, Poland
Anna Błażewicz: Department of Analytical Chemistry, Medical University of Lublin, 20-093 Lublin, Poland

IJERPH, 2021, vol. 18, issue 3, 1-9

Abstract: In view of previous reports, it is important to determine the relationship between liver function and the level of fluoride in the serum. The aim of this study was to investigate serum concentrations of fluoride in 72 patients with alcoholic liver cirrhosis, living in the region of Lublin (Eastern Poland) divided based on the severity of disease according to the Child-Turcotte-Pugh criteria. Higher plasma fluoride concentrations were associated with changes in liver related parameters. In all groups of analyzed patients with different stages of alcoholic liver cirrhosis, elevated levels of plasma fluoride and increased activities of both alanine aminotransferase (ALT) and total bilirubin concentration were shown.

Keywords: alcohol; liver cirrhosis; fluoride; ion chromatography (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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