Effects of General Physical Activity Promoting Interventions on Functional Outcomes in Patients Hospitalized over 48 Hours: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Joost P. H. Seeger, Niek Koenders, J. Bart Staal and Thomas J. Hoogeboom
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Joost P. H. Seeger: Research Group Musculoskeletal Rehabilitation, HAN University of Applied Sciences, 6825 EN Nijmegen, The Netherlands
Niek Koenders: Department of Rehabilitation, Radboud Institute for Health Sciences, Radboud University Medical Center, 6525 GC Nijmegen, The Netherlands
J. Bart Staal: Research Group Musculoskeletal Rehabilitation, HAN University of Applied Sciences, 6825 EN Nijmegen, The Netherlands
Thomas J. Hoogeboom: IQ Healthcare, Radboud Institute for Health Sciences, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands

IJERPH, 2021, vol. 18, issue 3, 1-13

Abstract: Low physical activity of patients is a global problem and associated with loss of strength and independent mobility. This study analyzes the effect of general physical activity promoting interventions on functional and hospital outcomes in patients hospitalized over 48 h. Five electronic databases were searched for randomized controlled trials. For outcomes reported in two studies or more, a meta-analysis was performed to test between-group differences (intervention versus control) using a random-effects model. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was used to rate the certainty of evidence for each outcome. Out of 23,302 identified studies, we included four studies (in total n = 368 participants). We found with moderate certainty of evidence 0 reported falls in the intervention ( n = 126) versus five reported falls in the control ( n = 122), a non-statistically significant difference between intervention and control groups ( p = 0.06). In addition, we found with (very) low certainty of evidence no statistically significant differences between groups on activities of daily living (ADL-activity) and time spent standing and walking. Overall, we found no conclusive evidence on the effect of general physical activity promoting interventions on functional outcomes. More research is needed to understand and improve the effect of general physical activity promoting interventions for patients during the hospital stay.

Keywords: physical activity; physical functioning; exercising; walking; mobilization; mobility; length of stay; hospitalization (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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