The Use of Artificial Hypoxia in Endurance Training in Patients after Myocardial Infarction

Agata Nowak-Lis, Tomasz Gabryś, Zbigniew Nowak, Paweł Jastrzębski, Urszula Szmatlan-Gabryś, Anna Konarska, Dominika Grzybowska-Ganszczyk and Anna Pilis
Additional contact information
Agata Nowak-Lis: Department of Physiotherapy, Jerzy Kukuczka’s Academy of Physical Education, 40-065 Katowice, Poland
Tomasz Gabryś: Sport Centrum Faculty of Pedagogy, University of West Bohemia, 301 00 Pilsen, Czech Republic
Zbigniew Nowak: Department of Physiotherapy, Jerzy Kukuczka’s Academy of Physical Education, 40-065 Katowice, Poland
Paweł Jastrzębski: Upper Silesian Medical Center, Cardiology Ward, 43-400 Cieszyn, Poland
Urszula Szmatlan-Gabryś: Department of Anatomy, Faculty of Rehabilitation University of Physical Education, 31-571 Krakow, Poland
Anna Konarska: Department of Physiotherapy, Jerzy Kukuczka’s Academy of Physical Education, 40-065 Katowice, Poland
Dominika Grzybowska-Ganszczyk: Department of Physiotherapy, Jerzy Kukuczka’s Academy of Physical Education, 40-065 Katowice, Poland
Anna Pilis: Faculty of Health Science, Jan Dlugosz University, 42-200 Czestochowa, Poland

IJERPH, 2021, vol. 18, issue 4, 1-11

Abstract: The presence of a well-developed collateral circulation in the area of the artery responsible for the infarction improves the prognosis of patients and leads to a smaller area of infarction. One of the factors influencing the formation of collateral circulation is hypoxia, which induces angiogenesis and arteriogenesis, which in turn cause the formation of new vessels. The aim of this study was to assess the effect of endurance training conducted under normobaric hypoxia in patients after myocardial infarction at the level of exercise tolerance and hemodynamic parameters of the left ventricle. Thirty-five patients aged 43–74 (60.48 ± 4.36) years who underwent angioplasty with stent implantation were examined. The program included 21 training units lasting about 90 min. A statistically significant improvement in exercise tolerance assessed with the cardiopulmonary exercise test (CPET) was observed: test duration ( p < 0.001), distance covered ( p < 0.001), HRmax ( p = 0.039), maximal systolic blood pressure (SBPmax) ( p = 0.044), peak minute ventilation (VE) ( p = 0.004) and breathing frequency (BF) ( p = 0.044). Favorable changes in left ventricular hemodynamic parameters were found for left ventricular end-diastolic dimension LVEDD ( p = 0.002), left ventricular end-systolic dimension LVESD ( p = 0.015), left ventricular ejection fraction (LVEF) ( p = 0.021), lateral e’ ( p < 0.001), septal e’ ( p = 0.001), and E/A ( p = 0.047). Endurance training conducted in hypoxic conditions has a positive effect on exercise tolerance and the hemodynamic indicators of the left ventricle.

Keywords: cardiac rehabilitation; endurance activity; normobaric hypoxia; exercise tolerance; left ventricle (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations: View citations in EconPapers (3)

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