The Development of a WTC Environmental Health Center Pan-Cancer Database

Yongzhao Shao, Nedim Durmus, Yian Zhang, Sultan Pehlivan, Maria-Elena Fernandez-Beros, Lisette Umana, Rachel Corona, Adrienne Addessi, Sharon A. Abbott, Sheila Smyth-Giambanco, Alan A. Arslan and Joan Reibman
Additional contact information
Yongzhao Shao: Division of Biostatistics, Department of Population Health, NYU Grossman School of Medicine (NYUGSOM), New York University, New York, NY 10016, USA
Nedim Durmus: World Trade Center Environmental Health Center, NYC Health + Hospitals, New York, NY 10016, USA
Yian Zhang: Division of Biostatistics, Department of Population Health, NYU Grossman School of Medicine (NYUGSOM), New York University, New York, NY 10016, USA
Sultan Pehlivan: World Trade Center Environmental Health Center, NYC Health + Hospitals, New York, NY 10016, USA
Maria-Elena Fernandez-Beros: World Trade Center Environmental Health Center, NYC Health + Hospitals, New York, NY 10016, USA
Lisette Umana: World Trade Center Environmental Health Center, NYC Health + Hospitals, New York, NY 10016, USA
Rachel Corona: World Trade Center Environmental Health Center, NYC Health + Hospitals, New York, NY 10016, USA
Adrienne Addessi: World Trade Center Environmental Health Center, NYC Health + Hospitals, New York, NY 10016, USA
Sharon A. Abbott: World Trade Center Environmental Health Center, NYC Health + Hospitals, New York, NY 10016, USA
Sheila Smyth-Giambanco: World Trade Center Environmental Health Center, NYC Health + Hospitals, New York, NY 10016, USA
Alan A. Arslan: Division of Biostatistics, Department of Population Health, NYU Grossman School of Medicine (NYUGSOM), New York University, New York, NY 10016, USA
Joan Reibman: Department of Environmental Medicine, NYUG-SOM, New York University, New York, NY 10016, USA

IJERPH, 2021, vol. 18, issue 4, 1-18

Abstract: (1) Background: Recent studies have reported elevated risks of multiple cancers in the World Trade Center (WTC) affected community members (also called WTC “Survivors”). The large variety of WTC-cancers created a need to develop a comprehensive cancer database. This paper describes the development of a pan-cancer database at the WTC Environmental Health Center (EHC) Data Center. (2) Methods: A new REDCap-based pan-cancer database was created using the pathology reports and available biomarker data of confirmed cancer cases after review by a cancer epidemiologist, a pathologist, physicians and biostatisticians. (3) Results: The WTC EHC pan-cancer database contains cancer characteristics and emerging biomarker information for cancers of individuals enrolled in the WTC EHC and diagnosed after 11 September 2001 and up to 31 December 2019 obtained from WTC EHC clinical records, pathological reports and state cancer registries. As of 31 December 2019, the database included 3440 cancer cases with cancer characteristics and biomarker information. (4) Conclusions: This evolving database represents an important resource for the scientific community facilitating future research about the etiology, heterogeneity, characteristics and outcomes of cancers and comorbid mental health conditions, cancer economics and gene–environment interaction in the unique population of WTC survivors.

Keywords: cancer incidence; biomarkers; WTC Environmental Health Center; September 11th; clinical cancer database; WTC survivors (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (9)

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