The Use of Middle Latency Auditory Evoked Potentials (MLAEP) as Methodology for Evaluating Sedation Level in Propofol-Drug Induced Sleep Endoscopy (DISE) Procedure

Michele Arigliani, Domenico M. Toraldo, Enrico Ciavolino, Caterina Lattante, Luana Conte, Serena Arima, Caterina Arigliani, Antonio Palumbo and Michele De Benedetto
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Michele Arigliani: ENT Unit, “V.Fazzi” Hospital, 73100 ASL Lecce, Italy
Domenico M. Toraldo: Department of Rehabilitation, Cardiorespiratory Rehabilitation Unit, “V.Fazzi” Hospital, 73100 ASL Lecce, Italy
Enrico Ciavolino: Department of History, Society and Human Studies, University of Salento, 73100 Lecce, Italy
Caterina Lattante: Anesthesia and Intensive Care Department, “V.Fazzi” Hospital, 73100 ASL Lecce, Italy
Luana Conte: Laboratory of Interdisciplinary Research Applied to Medicine (DReAM), University of Salento and ASL (Local Health Authority) at the “V Fazzi” Hospital, 73100 Lecce, Italy
Serena Arima: Department of History, Society and Human Studies, University of Salento, 73100 Lecce, Italy
Caterina Arigliani: General Medicine Department, Univerzita Pavla Jozefa Safarika, 04001 Kosiciach, Slovakia
Antonio Palumbo: ENT Unit, “V.Fazzi” Hospital, 73100 ASL Lecce, Italy
Michele De Benedetto: ENT Unit, “V.Fazzi” Hospital, 73100 ASL Lecce, Italy

IJERPH, 2021, vol. 18, issue 4, 1-12

Abstract: To analyze the middle latency auditory evoked potential index (MLAEPi), compared to the standard bispectral index (BIS), as a method for evaluating the sedation level in drug-induced sleep endoscopy (DISE). In this controlled clinical study on a sample of 99 obstructive sleep apnea (OSA) or snoring patients, we compared the MLAEPi with the BIS after propofol infusion during the standard DISE technique in order to define the MLAEPi values within the observational window of the procedure. The DISE procedure was divided into eight steps, and we collected both MLAEPi and BIS data values from the same patient in every step. The MLAEPi showed a faster response than the BIS after propofol infusion during DISE. Therefore, the clinical use of the MLAEPi in evaluating the sedation level seems to be a good alternative to the current technological standards.

Keywords: middle latency auditory evoked potentials; propofol; drug-induced sleep endoscopy; MLAEP index; bispectral index; obstructive sleep apnea; positive airway pressure; auditory evoked potentials; central sleep apnea (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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