Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides

Mar Requena-Mullor, Angeles Navarro-Mena, Ruqiong Wei, Olga López-Guarnido, David Lozano-Paniagua and Raquel Alarcon-Rodriguez
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Mar Requena-Mullor: Department of Nursing, Physiotherapy and Medicine, University of Almería, 04120 Almería, Spain
Angeles Navarro-Mena: Nursing Department, Torrecardenas Hospital, 04009 Almeria, Spain
Ruqiong Wei: Department of Rehabilitation Medicine, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China
Olga López-Guarnido: Department of Legal Medicine and Toxicology, Medical School, University of Granada, 18016 Granada, Spain
David Lozano-Paniagua: Department of Nursing, Physiotherapy and Medicine, University of Almería, 04120 Almería, Spain
Raquel Alarcon-Rodriguez: Department of Nursing, Physiotherapy and Medicine, University of Almería, 04120 Almería, Spain

IJERPH, 2021, vol. 18, issue 5, 1-11

Abstract: Although there are studies that show that some pesticides produce gonadal dysfunction and gonadal cancer in different animals, there are not many studiesregardinghumans. This study determined the prevalence and risk in humans of developing ovarian or testicular dysfunction or cancer in areas with distinct exposure to pesticides, which have endocrine disrupting properties. A population-based case-control study was carried out on humans living in ten health districts of Andalusia (Southern Spain) classified as areas of high or low environmental exposure to pesticides according to agronomic criteria. The study population included 5332 cases and 13,606 controls. Data were collected from computerized hospital records between 2000 and 2018.The risk of gonadal dysfunction or cancer was significantly higher in areas with higher use of pesticides in relation to those with lower use.

Keywords: pesticide; endocrine disruption; gonadal dysfunction; ovarian cancer; testicular cancer (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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