Adjusted Indirect and Mixed Comparisons of Interventions for the Patient-Reported Outcomes Measures (PROMs) of Disabled Adults: A Systematic Review and Network Meta-Analysis

Yining Xu, Xin Li, Zhihong Sun, Yang Song, Julien S. Baker and Yaodong Gu
Additional contact information
Yining Xu: Faculty of Sports Science, Ningbo University, Ningbo 315211, China
Xin Li: Research Academy of Grand Health, Ningbo University, Ningbo 315211, China
Zhihong Sun: Faculty of Sports Science, Ningbo University, Ningbo 315211, China
Yang Song: Faculty of Engineering, University of Szeged, 6724 Szeged, Hungary
Julien S. Baker: Centre for Health and Exercise Science Research, Department of Sport, Physical Education and Health, Hong Kong Baptist University, Hong Kong, China
Yaodong Gu: Faculty of Sports Science, Ningbo University, Ningbo 315211, China

IJERPH, 2021, vol. 18, issue 5, 1-29

Abstract: This systematic review adopted the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement (PRISMA) guidelines and used the method of network meta-analysis to compare the effects of different types of interventions from different perspectives which were abilities of daily life activity, psychological health, social functioning, and overall life quality. The eligibility criteria were: (1) Participants were adults above 18 years old with disabilities; (2) Interventions could be classified into active exercise, passive therapy, psychological education, psychosocial support program, multi-disciplinary program, and usual care; (3) Outcomes should be the patient-reported outcome measures (PROMs) that could be classified into abilities of daily life activity, psychological health, social functioning, and overall life quality; (4) Randomized designed and published in English. The keywords and their search field were: (1) “people with disabilities/disability”, “disabled”, “handicapped”, or “disable people” in titles or abstracts; (2) AND “randomized” or “randomised” in titles or abstracts; (3) NOT “design”, “protocol”, or “review” in titles. After searching in databases of Medline (EBSCO), PubMed, CINAHL, and Ovid, 16 studies were included. As a result, active exercise and passive therapy are most likely to be the best interventions for overall life quality, psychological education and passive therapy are most likely to be the best interventions for abilities of daily life activity, and psychosocial support programs are most likely to be the best intervention for psychological health and social functioning.

Keywords: people with disabilities; disabled; handicap; patient-reported outcome measures; network meta-analysis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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