Value Frameworks: Adaptation of Korean Versions of Value Frameworks for Oncology

Green Bae, SeungJin Bae, Donghwan Lee, Juhee Han, Dong-Hoe Koo, Do Yeun Kim, Hee-Jun Kim, Sung Young Oh, Hee Yeon Lee, Jong Hwan Lee, Hye Sook Han, Hyerim Ha and Jin Hyoung Kang
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Green Bae: College of Pharmacy, Ewha Womans University, Seoul 03760, Korea
SeungJin Bae: College of Pharmacy, Ewha Womans University, Seoul 03760, Korea
Donghwan Lee: Department of Statistics, Ewha Womans University, Seoul 03760, Korea
Juhee Han: College of Pharmacy, Ewha Womans University, Seoul 03760, Korea
Dong-Hoe Koo: Division of Hematology/Oncology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03063, Korea
Do Yeun Kim: Division of Hematology/Oncology, Department of Internal Medicine, Dongguk University Ilsan Hospital, Seoul 10326, Korea
Hee-Jun Kim: Division of Hematology/Medical Oncology, Department of Internal Medicine, Chung-Ang University Hospital, Seoul 06974, Korea
Sung Young Oh: Department of Internal Medicine, Dong-A University Hospital, Dong-A University College of Medicine, Busan 49236, Korea
Hee Yeon Lee: Division of Oncology, Department of Internal Medicine, Yeouido St. Mary’s Hospital, The Catholic University of Korea, Seoul 07345, Korea
Jong Hwan Lee: Department of Pharmaceutical Benefits, Health Insurance Review & Assessment, Wonju 26465, Korea
Hye Sook Han: Department of Internal Medicine, College of Medicine, Chungbuk National University, Cheongju 28644, Korea
Hyerim Ha: Division of Hematology & Oncology, Department of Internal Medicine, Inha University Hospital, Incheon 400 711, Korea
Jin Hyoung Kang: Medical Oncology, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul 07345, Korea

IJERPH, 2021, vol. 18, issue 6, 1-10

Abstract: This study sought to adapt the existing value framework (VF) to produce a reliable and valid Korean oncology VF. Two VFs developed by The American Society of Clinical Oncology (ASCO) and the European Society for Medical Oncology (ESMO) were selected for examination in the present study. Forward and backward translations were conducted for six high-priced drugs indicated for non-small-cell lung cancer and multiple myeloma. Inter-rater reliability was measured based on the intraclass correlation coefficient (ICC) and variation was described using the coefficient of variation. The relative weights of factors critically considered by Korean oncologists were derived following the analytic hierarchy process (AHP), and focus group interviews (FGIs) were used to obtain qualitative data regarding the applications of these two VFs in the Korean setting. The ICCs of the Korean VFs were 0.895 (0.654–0.983) for ASCO and 0.726 (0–0.982) for ESMO translations, suggesting excellent reliability for ASCO and good reliability for ESMO. AHP demonstrated that clinical benefit has the highest priority, which is consistent with the ASCO VF. The FGIs suggested that the result for AHP is acceptable and that both ESMO and ASCO VFs should be used complementarily. Although further evaluation with a larger sample size is needed, the Korean versions of ESMO/ASCO VFs are valid and reliable tools and are acceptable to Korean stakeholders, yet they should be applied with caution.

Keywords: oncology; value frameworks; country adaptation (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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