Hypertensive Disorders during Pregnancy (HDP), Maternal Characteristics, and Birth Outcomes among Japanese Women: A Hokkaido Study

Kritika Poudel, Sumitaka Kobayashi, Chihiro Miyashita, Atsuko Ikeda-Araki, Naomi Tamura, Yu Ait Bamai, Sachiko Itoh, Keiko Yamazaki, Hideyuki Masuda, Mariko Itoh, Kumiko Ito and Reiko Kishi
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Kritika Poudel: Faculty of Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Sumitaka Kobayashi: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Chihiro Miyashita: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Atsuko Ikeda-Araki: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Naomi Tamura: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Yu Ait Bamai: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Sachiko Itoh: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Keiko Yamazaki: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Hideyuki Masuda: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Mariko Itoh: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Kumiko Ito: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
Reiko Kishi: Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan

IJERPH, 2021, vol. 18, issue 7, 1-16

Abstract: Hypertension during pregnancy causes a greater risk of adverse birth outcomes worldwide; however, formal evidence of hypertensive disorders during pregnancy (HDP) in Japan is limited. We aimed to understand the association between maternal characteristics, HDP, and birth outcomes. In total, 18,833 mother-infant pairs were enrolled in the Hokkaido study on environment and children’s health, Japan, from 2002 to 2013. Medical records were used to identify hypertensive disorders and birth outcomes, namely, small for gestational age (SGA), SGA at full term (term-SGA), preterm birth (PTB), and low birth weight (LBW). The prevalence of HDP was 1.9%. Similarly, the prevalence of SGA, term-SGA, PTB, and LBW were 7.1%, 6.3%, 7.4%, and 10.3%, respectively. The mothers with HDP had increased odds of giving birth to babies with SGA (2.13; 95% Confidence Interval (CI): 1.57, 2.88), PTB (3.48; 95%CI: 2.68, 4.50), LBW (3.57; 95%CI: 2.83, 4.51) than normotensive pregnancy. Elderly pregnancy, low and high body mass index, active and passive smoking exposure, and alcohol consumption were risk factors for different birth outcomes. Therefore, it is crucial for women of reproductive age and their families to be made aware of these risk factors through physician visits, health education, and various community-based health interventions.

Keywords: hypertensive disorders during pregnancy; mothers; birth outcomes; cohort study (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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