Association of Air Pollutants with Incident Chronic Kidney Disease in a Nationally Representative Cohort of Korean Adults

Seo Yun Hwang, Seogsong Jeong, Seulggie Choi, Dong Hyun Kim, Seong Rae Kim, Gyeongsil Lee, Joung Sik Son and Sang Min Park
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Seo Yun Hwang: School of Health and Environmental Science, Korea University, Seoul 02841, Korea
Seogsong Jeong: Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea
Seulggie Choi: Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea
Dong Hyun Kim: Department of Medicine, Seoul National University College of Medicine, Seoul 03080, Korea
Seong Rae Kim: Department of Medicine, Seoul National University College of Medicine, Seoul 03080, Korea
Gyeongsil Lee: Department of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea
Joung Sik Son: Department of Family Medicine, Korea University Guro Hospital, Seoul 08308, Korea
Sang Min Park: Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea

IJERPH, 2021, vol. 18, issue 7, 1-10

Abstract: (1) Background: There is limited information regarding association between long-term exposure to air pollutants and risk of chronic kidney disease (CKD) (2). Methods: This study acquired data of 164,093 adults aged at least 40 years who were residing in 7 metropolitan cities between 2002 and 2005 from the Korean National Health Insurance Service National Sample Cohort database. CKD risk was evaluated using the multivariate Cox hazards proportional regression. All participants were followed up with until CKD, death, or 31 December 2013, whichever occurred earliest. (3) Results: Among 1,259,461 person-years of follow-up investigation, CKD cases occurred in 1494 participants. Air pollutant exposures including PM 10 , SO 2 , NO 2 , CO, and O 3 showed no significant association with incident CKD after adjustments for age, sex, household income, area of residence, and the Charlson comorbidity index. The results were consistent in the sensitivity analyses including first and last year annual exposure analyses as well as latent periods-washed-out analyses. (4) Conclusions: Long-term exposure to air pollution is not likely to increase the risk of CKD.

Keywords: particulate matter; renal failure; air pollution; ozone; cohort study (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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