Increased Incidence of Premenstrual Syndrome in Females with Palmar Hyperhidrosis

Chun-An Cheng, Yu-Cheng Liang, Yin-Han Chang, Chun-Gu Cheng, Chi-Hsiang Chung and Wu-Chien Chien
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Chun-An Cheng: Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan
Yu-Cheng Liang: Department of Information, Taiwan Fertilizer Company, Taipei 10457, Taiwan
Yin-Han Chang: Department of Psychology, National Taiwan University, Taipei 10621, Taiwan
Chun-Gu Cheng: Department of Emergency Medicine, Taoyuan Armed Force General Hospital, National Defense Medical Center, Taoyuan 32549, Taiwan
Chi-Hsiang Chung: Department of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan
Wu-Chien Chien: Department of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan

IJERPH, 2021, vol. 18, issue 9, 1-11

Abstract: Background: Premenstrual syndrome (PMS) is a common disorder affecting the quality of life of women of reproductive age. In a previous study, sex hormone imbalances and alterations in autonomic function were present in PMS, with parasympathetic dysfunction and sympathetic overactivity during the late luteal phase. Palmar hyperhidrosis (PH) presents with oversweating, heat and emotional stimulation, sympathetic hyperactivity and parasympathetic hypofunction. We hypothesized that the incidence of PMS is increased in females with PH. Methods: Data were retrieved from the Taiwanese National Health Insurance Database. The patients with PH were identified by the International Classification of Disease, 9th Revision, Clinical Modification (ICD-9-CM) disease code 780.8. Female patients matched by age and index day were used as the control group. The incidence of PMS was considered an outcome by the ICD-9-CM disease code 625.4. The factors related to PMS were analyzed by Cox regression. Results: The adjusted hazard ratio for the incidence of PMS was 1.276 (95% confidence interval: 1.05–1.488) in females with PH. Conclusions: This study found a positive correlation between PMS and female PH patients. Patients and physicians must understand the relationship of PMS with autonomic function alterations and other risk factors to prevent this problematic disorder.

Keywords: autonomic dysfunction; premenstrual syndrome; palmar hyperhidrosis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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