Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective

Marta Mazur, Irena Duś-Ilnicka, Maciej Jedliński, Artnora Ndokaj, Joanna Janiszewska-Olszowska, Roman Ardan, Malgorzata Radwan-Oczko, Fabrizio Guerra, Valeria Luzzi, Iole Vozza, Roberto Marasca, Livia Ottolenghi and Antonella Polimeni
Additional contact information
Marta Mazur: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy
Irena Duś-Ilnicka: Department of Oral Pathology, Wroclaw Medical University, ul. Krakowska 26, 52-425 Wrocław, Poland
Maciej Jedliński: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy
Artnora Ndokaj: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy
Joanna Janiszewska-Olszowska: Department of Interdisciplinary Dentistry, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland
Roman Ardan: Department of Economic Sciences, Koszalin University of Technology, 75-343 Koszalin, Poland
Malgorzata Radwan-Oczko: Department of Oral Pathology, Wroclaw Medical University, ul. Krakowska 26, 52-425 Wrocław, Poland
Fabrizio Guerra: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy
Valeria Luzzi: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy
Iole Vozza: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy
Roberto Marasca: Paediatric Dentistry Unit, Head and Neck Integrated Department, AOU Policlinico Umberto I of Rome, Viale Regina Elena 287/b, 00161 Rome, Italy
Livia Ottolenghi: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy
Antonella Polimeni: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy

IJERPH, 2021, vol. 18, issue 9, 1-11

Abstract: (1) Background: Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) emerged in Wuhan, China, in late 2019. The development of effective and safe vaccines against SARS-CoV-2 has been extremely fast. The list of orofacial adverse effects of BNT162b2 and mRNA-1273 vaccines based on the clinical trials are reported to be rare. The aim of this study was to investigate the facial and oral manifestations of COVID-19 vaccination using a survey-based study. (2) Methods: The questionnaire was developed using Google Forms and sent anonymously to a total of 700 subjects (medical personnel) in Poland, Italy, and other EU countries. (3) Results: 223 people answered the questionnaire, mainly vaccinated with BNT162b2. Only 3.1% and 5.4% experienced oral and facial symptoms, respectively. General diseases presence and age have significant influence on the probability of oral symptoms occurrence after the second dose. Facial symptoms are correlated with general disease; autoimmune pathologies and age, at first and second dose, respectively. Gender, smoking and regular medication intake have significant influence on the probability of taking an absence day. Gender, age, and smoking have a significant influence on the duration of symptoms after second dose. (4) Conclusions: Based on the results of this preliminary survey, there is no observed significant correlation between vaccine administration for COVID-19 and facial and oral manifestations.

Keywords: COVID-19; COVID-19 vaccines; vaccines; BNT162b2; mRNA-1273; survey; questionnaire; oral signs; facial signs; orofacial manifestations (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations: View citations in EconPapers (3)

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