Perinatal Environmental Health Education Intervention to Reduce Exposure to Endocrine Disruptors: The PREVED Project

Houria El Ouazzani, Simon Fortin, Nicolas Venisse, Antoine Dupuis, Steeve Rouillon, Guillaume Cambien, Anne-Sophie Gourgues, Pascale Pierre-Eugène, Sylvie Rabouan, Virginie Migeot and Marion Albouy-Llaty
Additional contact information
Houria El Ouazzani: Center of Clinical Investigation Inserm 1402, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France
Simon Fortin: Center of Clinical Investigation Inserm 1402, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France
Nicolas Venisse: Center of Clinical Investigation Inserm 1402, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France
Antoine Dupuis: Center of Clinical Investigation Inserm 1402, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France
Steeve Rouillon: APHP Laboratory of Pharmacology, GH Henri Mondor, 94010 Creteil, France
Guillaume Cambien: Center of Clinical Investigation Inserm 1402, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France
Anne-Sophie Gourgues: BioSPharm Pole, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France
Pascale Pierre-Eugène: Center of Clinical Investigation Inserm 1402, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France
Sylvie Rabouan: Center of Clinical Investigation Inserm 1402, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France
Virginie Migeot: Center of Clinical Investigation Inserm 1402, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France
Marion Albouy-Llaty: Center of Clinical Investigation Inserm 1402, University Hospital of Poitiers, 2 Rue de la Milétrie, 86021 Poitiers, France

IJERPH, 2021, vol. 19, issue 1, 1-28

Abstract: Environmental health promotion interventions may reduce endocrine disruptor (ED) exposure. The PREVED (PREgnancy, preVention, Endocrine Disruptors) project was developed to improve knowledge, to enhance risk perception, and to change exposure behavior. Our objective was to present the phases of the PREVED project using the RE-AIM method. PREVED intervention consisted of three workshops during pregnancy. Reach, adoption, and implementation phases were assessed with qualitative studies. Efficacy study consisted of a three-arm randomized controlled trial (RCT) on 268 pregnant women: (i) control group (leaflet), (ii) intervention group in neutral location, (iii) intervention group in contextualized location. The main outcome was the percentage evolution of participants who reported consuming canned food. Secondary outcomes were evolution of psycho-social scores, evolution of ED presence in urine, and ED presence in colostrum. The intervention adoption was centered on upper-privileged women, but implementation assessment showed that key features (highly practical intervention) seemed to be carried out and had initiated some behavior changes. A total of 268 pregnant women participated in the intervention and 230 in a randomized controlled trial (control group: 86 and intervention groups: 172). We found no significant differences in consumption of canned food and in percentage of women having a decrease of bisphenol A or parabens in urine, but we found a significant increase in the evolution of risk perception score and overall psychosocial score in intervention groups (respectively: +15.73 control versus +21.03 intervention, p = 0.003 and +12.39 versus +16.20, p = 0.02). We found a significant difference in percentage of women with butylparaben detection between control group and intervention groups (13% versus 3%, p = 0.03). PREVED intervention is the first intervention research dedicated to perinatal environmental health education in France. By sharing know-how/experience in a positive non-alarmist approach, it improved risk perception, which is key to behavior change, aiming to reduce perinatal ED exposure. Including women in precarious situations remains a major issue.

Keywords: environmental health promotion; pregnancy; endocrine disruptors; lifestyle change intervention; RE-AIM; bisphenol A; parabens (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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