Increased Risk of COVID-19 in Patients with Diabetes Mellitus—Current Challenges in Pathophysiology, Treatment and Prevention

Tomasz Gęca, Kamila Wojtowicz, Paweł Guzik and Tomasz Góra
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Tomasz Gęca: Chair and Department of Obstetrics and Pathology of Pregnancy, Medical University of Lublin, 20-081 Lublin, Poland
Kamila Wojtowicz: Clinical Department of Gynecology and Obstetrics, John Paul’s 2nd Municipal Hospital, 35-241 Rzeszow, Poland
Paweł Guzik: Clinical Department of Gynecology and Obstetrics, John Paul’s 2nd Municipal Hospital, 35-241 Rzeszow, Poland
Tomasz Góra: Clinical Department of Gynecology and Obstetrics, John Paul’s 2nd Municipal Hospital, 35-241 Rzeszow, Poland

IJERPH, 2022, vol. 19, issue 11, 1-17

Abstract: Coronavirus disease—COVID-19 (coronavirus disease 2019) has become the cause of the global pandemic in the last three years. Its etiological factor is SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus type 2). Patients with diabetes (DM—diabetes mellitus), in contrast to healthy people not suffering from chronic diseases, are characterised by higher morbidity and mortality due to COVID-19. Patients who test positive for SARCoV-2 are at higher risk of developing hyperglycaemia. In this paper, we present, analyse and summarize the data on possible mechanisms underlying the increased susceptibility and mortality of patients with diabetes mellitus in the case of SARS-CoV-2 infection. However, further research is required to determine the optimal therapeutic management of patients with diabetes and COVID-19.

Keywords: COVID-19; diabetes mellitus; SARS-CoV-2; oxidative stress; angiotensin converting enzyme-2 (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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