The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up

Rodrigo Núñez-Cortés, Constanza Malhue-Vidal, Florencia Gath, Gonzalo Valdivia-Lobos, Rodrigo Torres-Castro, Carlos Cruz-Montecinos, Francisco M. Martinez-Arnau, Sofía Pérez-Alenda, Rubén López-Bueno and Joaquín Calatayud
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Rodrigo Núñez-Cortés: Physiotherapy in Motion Multispeciality Research Group (PTinMOTION), Department of Physiotherapy, University of Valencia, 46010 Valencia, Spain
Constanza Malhue-Vidal: Service of Physical Therapy, Hospital Clínico La Florida, Santiago 8240000, Chile
Florencia Gath: Service of Physical Therapy, Hospital Clínico La Florida, Santiago 8240000, Chile
Gonzalo Valdivia-Lobos: Service of Physical Therapy, Hospital Clínico La Florida, Santiago 8240000, Chile
Rodrigo Torres-Castro: Department of Physical Therapy, Faculty of Medicine, University of Chile, Santiago 8380286, Chile
Carlos Cruz-Montecinos: Physiotherapy in Motion Multispeciality Research Group (PTinMOTION), Department of Physiotherapy, University of Valencia, 46010 Valencia, Spain
Francisco M. Martinez-Arnau: Physiotherapy in Motion Multispeciality Research Group (PTinMOTION), Department of Physiotherapy, University of Valencia, 46010 Valencia, Spain
Sofía Pérez-Alenda: Physiotherapy in Motion Multispeciality Research Group (PTinMOTION), Department of Physiotherapy, University of Valencia, 46010 Valencia, Spain
Rubén López-Bueno: Department of Physical Medicine and Nursing, University of Zaragoza, 50009 Zaragoza, Spain
Joaquín Calatayud: National Research Centre for the Working Environment, 2100 Copenhagen, Denmark

IJERPH, 2022, vol. 19, issue 12, 1-9

Abstract: Objective: To determine the association between the Charlson comorbidity index (CCI) score after discharge with 6-min walk test (6MWT) 1 year after discharge in a cohort of COVID-19 survivors. Methods: In this prospective study, data were collected from a consecutive sample of patients hospitalized for COVID-19. The CCI score was calculated from the comorbidity data. The main outcome was the distance walked in the 6MWT at 1 year after discharge. Associations between CCI and meters covered in the 6MWT were assessed through crude and adjusted linear regressions. The model was adjusted for possible confounding factors (sex, days of hospitalization, and basal physical capacity through sit-to-stand test one month after discharge). Results: A total of 41 patients were included (mean age 58.8 ± 12.7 years, 20/21 men/women). A significant association was observed between CCI and 6MWT (meters): (i) crude model: β = −18.7, 95% CI = −34.7 to −2.6, p < 0.05; (ii) model adjusted for propensity score including sex, days of hospitalization, and sit-to-stand: β = −23.0, 95% CI = −39.1 to −6.8, p < 0.05. Conclusions: A higher CCI score after discharge indicates worse performance on the 6MWT at 1-year follow-up in COVID-19 survivors. The CCI score could also be used as a screening tool to make important clinical decisions.

Keywords: coronavirus disease 2019; physical capacity; six-minute walk test; comorbidity (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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