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Skin Toxicity of Selected Hair Cosmetic Ingredients: A Review Focusing on Hairdressers

Cara Symanzik, Patricia Weinert, Željka Babić, Sarah Hallmann, Martin Stibius Havmose, Jeanne Duus Johansen, Sanja Kezic, Marija Macan, Jelena Macan, Julia Strahwald, Rajka Turk, Henk F. van der Molen, Swen Malte John and Wolfgang Uter
Additional contact information
Cara Symanzik: Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) and Department of Dermatology, Environmental Medicine and Health Theory, Osnabrück University, 49076 Osnabrueck, Germany
Patricia Weinert: Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) and Department of Dermatology, Environmental Medicine and Health Theory, Osnabrück University, 49076 Osnabrueck, Germany
Željka Babić: Institute for Medical Research and Occupational Health, HR 10001 Zagreb, Croatia
Sarah Hallmann: Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen, 91054 Erlangen, Germany
Martin Stibius Havmose: National Allergy Research Centre, Department of Skin and Allergy, University of Copenhagen, Gentofte Hospital, 2900 Copenhagen, Denmark
Jeanne Duus Johansen: National Allergy Research Centre, Department of Skin and Allergy, University of Copenhagen, Gentofte Hospital, 2900 Copenhagen, Denmark
Sanja Kezic: Amsterdam UMC, Department of Public and Occupational Health, Coronel Institute of Occupational Health, Amsterdam Public Health Research Institute, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Marija Macan: Institute for Medical Research and Occupational Health, HR 10001 Zagreb, Croatia
Jelena Macan: Institute for Medical Research and Occupational Health, HR 10001 Zagreb, Croatia
Julia Strahwald: Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen, 91054 Erlangen, Germany
Rajka Turk: Institute for Medical Research and Occupational Health, HR 10001 Zagreb, Croatia
Henk F. van der Molen: Amsterdam UMC, Department of Public and Occupational Health, Coronel Institute of Occupational Health, Amsterdam Public Health Research Institute, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Swen Malte John: Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) and Department of Dermatology, Environmental Medicine and Health Theory, Osnabrück University, 49076 Osnabrueck, Germany
Wolfgang Uter: Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen, 91054 Erlangen, Germany

IJERPH, 2022, vol. 19, issue 13, 1-25

Abstract: The safety assessment of cosmetics considers the exposure of a ‘common consumer’, not the occupational exposure of hairdressers. This review aims to compile and appraise evidence regarding the skin toxicity of cysteamine hydrochloride (cysteamine HCl; CAS no. 156-57-0), polyvinylpyrrolidone (PVP; CAS no. 9003-39-8), PVP copolymers (CAS no. 28211-18-9), sodium laureth sulfate (SLES; CAS no. 9004-82-4), cocamide diethanolamine (cocamide DEA; CAS no. 68603-42-9), and cocamidopropyl betaine (CAPB; CAS no. 61789-40-0). A total of 298 articles were identified, of which 70 were included. Meta-analysis revealed that hairdressers have a 1.7-fold increased risk of developing a contact allergy to CAPB compared to controls who are not hairdressers. Hairdressers might have a higher risk of acquiring quantum sensitization against cysteamine HCl compared to a consumer because of their job responsibilities. Regarding cocamide DEA, the irritant potential of this surfactant should not be overlooked. Original articles for PVP, PVP copolymers, and SLES are lacking. This systematic review indicates that the current standards do not effectively address the occupational risks associated with hairdressers’ usage of hair cosmetics. The considerable irritant and/or allergenic potential of substances used in hair cosmetics should prompt a reassessment of current risk assessment practices.

Keywords: cysteamine hydrochloride; cocamide diethanolamine; cocamidopropyl betaine; cosmetics; hairdresser; hairdressing; hand eczema; polyvinylpyrrolidone; polyvinylpyrrolidone copolymers; sodium laureth sulfate (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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