Ventilatory Muscle Training for Early Cardiac Rehabilitation Improved Functional Capacity and Modulated Vascular Function of Individuals Undergoing Coronary Artery Bypass Grafting: Pilot Randomized Clinical Trial

Bruna Eibel, Juliana R. Marques, Thiago Dipp, Gustavo Waclawovsky, Rafael A. Marschner, Liliana C. Boll, Renato A. K. Kalil, Alexandre M. Lehnen, Allan R. K. Sales and Maria Claudia Costa Irigoyen
Additional contact information
Bruna Eibel: Instituto de Cardiologia/Fundação, Universitária de Cardiologia (IC/FUC), Porto Alegre 90040-371, RS, Brazil
Juliana R. Marques: Instituto de Cardiologia/Fundação, Universitária de Cardiologia (IC/FUC), Porto Alegre 90040-371, RS, Brazil
Thiago Dipp: Programa de Pós-Graduação em Saúde Coletiva, Universidade do Vale do Rio dos Sinos (UNISINOS), São Leopoldo 93022-750, RS, Brazil
Gustavo Waclawovsky: Instituto de Cardiologia/Fundação, Universitária de Cardiologia (IC/FUC), Porto Alegre 90040-371, RS, Brazil
Rafael A. Marschner: Hospital de Clínicas de Porto Alegre (HCPA), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90035-903, RS, Brazil
Liliana C. Boll: Instituto de Cardiologia/Fundação, Universitária de Cardiologia (IC/FUC), Porto Alegre 90040-371, RS, Brazil
Renato A. K. Kalil: Instituto de Cardiologia/Fundação, Universitária de Cardiologia (IC/FUC), Porto Alegre 90040-371, RS, Brazil
Alexandre M. Lehnen: Instituto de Cardiologia/Fundação, Universitária de Cardiologia (IC/FUC), Porto Alegre 90040-371, RS, Brazil
Allan R. K. Sales: Institute DOR for Research and Education (IDOR), São Paulo 04501-000, SP, Brazil
Maria Claudia Costa Irigoyen: Instituto de Cardiologia/Fundação, Universitária de Cardiologia (IC/FUC), Porto Alegre 90040-371, RS, Brazil

IJERPH, 2022, vol. 19, issue 15, 1-10

Abstract: Background: Cardiac rehabilitation with aerobic exercises is the first strategy for nonpharmacological treatment in the postoperative period of individuals undergoing coronary artery bypass grafting (CABG) to improve functional capacity and vascular health. However, other exercise modalities remain uncertain regarding the same benefits. Objectives: Evaluation of the effect of different modalities of exercise, such as early cardiac rehabilitation on subjects submitted to CABG in the six-minute walk test (6-MWT) and on the percentage of flow-mediated dilatation (FMD) of the brachial artery. Methods: A randomized clinical trial in which 15 patients (62.7 ± 6.7 years) who underwent CABG were randomly assigned to the following groups: isometric (IG, Handgrip Jamar ® ), ventilatory muscle training (VG, PowerBreathe ® ) and control (CG, conventional respiratory and motor physiotherapy). All patients were attended to physically twice a day (20 min/session) for a consecutive week after the CABG (hospital admission). Functional capacity was assessed by 6-MWT and endothelial function was assessed through the technique of FMD, before and after (~7 days) admission to CABG. The doppler ultrasound videos were analyzed by Cardiovascular Suite ® software (Quipu, Pisa, Italy) to measure %FMD. Statistics: Generalized estimation equation, followed by Bonferroni post hoc ( p < 0.05). Results: Systolic, diastolic and mean arterial pressure (SBP/DBP/MAP, respectively) were 133, 76 and 95 mmHg. The groups presented walking meters (m) distance before and after intervention of: IG basal 357.80 ± 47.15 m vs. IG post 306.20 ± 61.63 m, p = 0.401 (+51 m); VG basal 261.50 ± 19.91 m vs. VG post 300.75 ± 26.29 m, p = 0.052 (+39 m); CG basal 487.83 ± 83.23 m vs. CG post 318.00 ± 31.08, p = 0.006 (−169 m). %FMD before and after intervention was IG basal 10.4 ± 4.8% vs. IG post 2.8 ± 2.5%, p = 0.152; VG basal 9.8 ± 5.1% vs. VG post 11.0 ± 6.1%, p = 0.825; CG basal 9.2 ± 15.8% vs. CG post 2.7 ± 2.6%, p = 0.710 and resting mean basal blood flow was IG basal 162.0 ± 55.0 mL/min vs. IG post 129.9 ± 63.7 mL/min, p = 0.662; VG basal 83.74 ± 12.4 mL/min vs. VG post 58.7 ± 17.1 mL/min, p = 0.041; CG basal 375.6 ± 183.7 mL/min vs. CG post 192.8 ± 115.0 mL/min, p = 0.459. Conclusions: Ventilatory muscle training for early cardiac rehabilitation improved acute functional capacity and modulated mean flow of individuals undergoing CABG.

Keywords: coronary artery bypass grafting; cardiac rehabilitation; functional capacity; flow-mediated dilatation (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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