Effect of Sinus Floor Augmentation with Platelet-Rich Fibrin Versus Allogeneic Bone Graft on Stability of One-Stage Dental Implants: A Split-Mouth Randomized Clinical Trial

Aida Karagah, Reza Tabrizi, Parinaz Mohammadhosseinzade, Monirsadat Mirzadeh, Maryam Tofangchiha, Carlo Lajolo and Romeo Patini
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Aida Karagah: Department of Oral and Maxillofacial Surgery, School of Dentistry, Qazvin University of Medical Sciences, Qazvin 34199-15315, Iran
Reza Tabrizi: Department of Oral and Maxillofacial Surgery, Shahid Beheshti University of Medical Sciences, Tehran 11151-19857, Iran
Parinaz Mohammadhosseinzade: Student Research Committee, Qazvin University of Medical Sciences, Qazvin 34199-15315, Iran
Monirsadat Mirzadeh: Metabolic Diseases Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin 34199-15315, Iran
Maryam Tofangchiha: Department of Oral and Maxillofacial Radiology, Dental Caries Prevention Research Center, Qazvin University of Medical Sciences, Qazvin 34199-15315, Iran
Carlo Lajolo: Department of Head, Neck and Sense Organs “Fondazione Policlinico Universitario A. Gemelli-IRCCS”, School of Dentistry, Catholic University of Sacred Heart, 00168 Rome, Italy
Romeo Patini: Department of Head, Neck and Sense Organs “Fondazione Policlinico Universitario A. Gemelli-IRCCS”, School of Dentistry, Catholic University of Sacred Heart, 00168 Rome, Italy

IJERPH, 2022, vol. 19, issue 15, 1-10

Abstract: Rehabilitation of an edentulous posterior maxilla with dental implants is challenging, and sinus floor augmentation could be considered as an important surgical procedure for bone augmentation in this region before implant placement. Platelet-rich fibrin (PRF) is a new-generation platelet concentrate with simplified processing: its application in sinus floor augmentation has been widely investigated in literature. However, the biological properties and actual efficacy of this product remain controversial. This study assessed the effect of sinus floor augmentation with PRF versus freeze-dried bone allograft (FDBA) on stability of one-stage dental implants. This split-mouth randomized clinical trial evaluated 10 patients who required bilateral sinus floor augmentation. PRF and L-PRF membrane were used in one quadrant while FDBA and collagen membrane were used in the other quadrant. Implant stability was assessed by resonance frequency analysis (RFA) immediately, and 2, 4, and 6 months after implant placement. The implant stability quotient (ISQ) was compared over time and between the two groups using repeated measures ANOVA and independent sample t -test. The mean ISQ significantly increased over time in both groups ( p < 0.001). The increase was greater in the PRF group ( p < 0.05). Within the limitations of this study, PRF yielded superior results compared with FDBA regarding the stability of one-stage dental implants.

Keywords: sinus floor augmentation; platelet rich fibrin; allograft; freeze-dried bone allograft; implant stability (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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