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Influence of Serum Vitamin D Levels on Survival Rate and Marginal Bone Loss in Dental Implants: A Systematic Review

Santiago Bazal-Bonelli, Luis Sánchez-Labrador, Jorge Cortés-Bretón Brinkmann, Carlos Cobo-Vázquez, Natalia Martínez-Rodríguez, Tomás Beca-Campoy, Juan Santos-Marino, Emilio Rodríguez-Fernández and Mario Alvarado-Lorenzo ()
Additional contact information
Santiago Bazal-Bonelli: Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, 28040 Madrid, Spain
Luis Sánchez-Labrador: Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, 28040 Madrid, Spain
Jorge Cortés-Bretón Brinkmann: Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, 28040 Madrid, Spain
Carlos Cobo-Vázquez: Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, 28040 Madrid, Spain
Natalia Martínez-Rodríguez: Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, 28040 Madrid, Spain
Tomás Beca-Campoy: Private Practice, 28006 Madrid, Spain
Juan Santos-Marino: Department of Surgery, Faculty of Medicine, University of Salamanca, 37008 Salamanca, Spain
Emilio Rodríguez-Fernández: Postgraduate Program in Oral Surgery, Implant and Restorative Dentistry, University of Cordoba, 14004 Cordoba, Spain
Mario Alvarado-Lorenzo: Postgraduate Program in Oral Surgery, Periodontics and Restorative Dentistry, San Antonio de Murcia Catholic University, 30107 Murcia, Spain

IJERPH, 2022, vol. 19, issue 16, 1-11

Abstract: This systematic literature review set out to investigate the relationship between serum vitamin D levels and dental implants in terms of survival rates, marginal bone loss, and associated complications. The review was conducted according to PRISMA guidelines, performing an electronic search in four databases (Pubmed, Web of Science, Cochrane, and Scopus), complemented by a manual search up to April 2022. Four articles were selected for analysis. The Newcastle-Ottawa Quality Assessment Scale tool was used to assess the quality of evidence of cohort studies, and the Cochrane bias assessment tool was used to assess the quality of evidence of randomized clinical trials. The study included 1089 patients restored with 1984 dental implants, with follow-up periods ranging from 20–240 months. Cases presenting lower serum vitamin D levels obtained slightly worse results in terms of marginal bone loss. Longer follow-up periods are needed in order to determine whether serum vitamin D levels affect implant survival rates and osseointegration over time.

Keywords: dental implant; vitamin D; osseointegration; bone resorption (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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