Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan

Min-Huei Hsu, Chia-An Hsu, Shih-Chung Lai and Ju-Chuan Yen ()
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Min-Huei Hsu: Graduate Institute of Data Science, College of Management, Taipei Medical University, Taipei 11042, Taiwan
Chia-An Hsu: Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 11217, Taiwan
Shih-Chung Lai: Department of Ophthalmology, Shuang Ho Hospital, Taipei Medical University, Taipei 23561, Taiwan
Ju-Chuan Yen: Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei 11042, Taiwan

IJERPH, 2022, vol. 19, issue 16, 1-9

Abstract: The relationship between gout and age-related macular degeneration (AMD) was suggested in previous literature but has yet to be accepted fully among physicians. This study aimed to explore the effect of gout on the development of age-related macular degeneration in Taiwan. A retrospective cohort study was conducted using Taiwan’s National Health Insurance Database that includes a 2-million-persons dataset. The crude hazard ratio, Kaplan–Meier plot, and separate cox proportional hazard ratio were utilized to demonstrate the effect of gout on the development of age-related macular degeneration. The crude hazard ratio for gout patients developing AMD was 1.55 and the adjusted hazard ratio 1.20. In conclusion, gout is a risk factor for developing AMD, and achieving good disease management is therefore essential for preventing AMD from occurring.

Keywords: age-related macular degeneration; gout; Taiwan National Health Insurance Research Database (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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