Association of Vegetable and Fruit Consumption with Urinary Oxidative Biomarkers in Teenaged Girls: A School-Based Pilot Study in Japan

Yoshiko Sato, Ai Yamada, Masamitsu Miyanaga and Da-Hong Wang ()
Additional contact information
Yoshiko Sato: Department of Bioscience, Faculty of Life Science, Okayama University of Science, Okayama 700-0005, Japan
Ai Yamada: Japan Industrial Safety and Health Association, Osaka 550-0001, Japan
Masamitsu Miyanaga: Department of Bioscience, Faculty of Life Science, Okayama University of Science, Okayama 700-0005, Japan
Da-Hong Wang: Department of Bioscience, Faculty of Life Science, Okayama University of Science, Okayama 700-0005, Japan

IJERPH, 2022, vol. 19, issue 17, 1-12

Abstract: Hexanoyl-lysine (HEL), 8-hydroxy-2′deoxyguanosine (8-OHdG), and dityrosine (DT) have served as potential biomarkers for detecting oxidative modified lipids, DNA, and proteins in biological samples, respectively. Whether regular higher levels of consumption of vegetables/fruit (V/F) would decrease oxidative modification of these biomolecules in the body remain unelucidated. To examine the association of regular V/F consumption with the generation of these reactive oxygen species-induced biomarkers, this study evaluated V/F consumption in a school-based sample of teenaged girls (mean age 15.6 ± 1.7 years, n = 103), and quantified the formation of oxidative stress biomarkers in their urine. Only 19.4% and 23.3% of participants reported that they consumed the recommended daily amount of vegetables and fruits, respectively. Individuals who consumed lower levels of fruit (<100g/day) or vegetables (<250g/day) had significantly higher HEL excretion in their urine than those who consumed higher levels of fruit (≥100g/day) ( p < 0.05) or vegetables (≥250g/day) ( p = 0.057). The results of a multiple regression analysis showed that vegetable consumption was an important inhibiting factor of early lipid peroxidation measured as HEL in urine, independent of various confounders (β = − 0.332, p < 0.05). The findings suggest that relatively higher consumption of vegetables would help in the prevention of early lipid peroxidation in adolescents.

Keywords: vegetable/fruit consumption; oxidative biomarkers; hexanoyl-lysine; 8-hydroxy-2?deoxyguanosine; dityrosine; hydrogen peroxide; physical exercise; urine; teenaged girls (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/19/17/10474/pdf (application/pdf)
https://www.mdpi.com/1660-4601/19/17/10474/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:19:y:2022:i:17:p:10474-:d:895156

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().