Risk Factors Attributable to Hypertension among HIV-Infected Patients on Antiretroviral Therapy in Selected Rural Districts of the Eastern Cape Province, South Africa

Urgent Tsuro, Kelechi E. Oladimeji, Guillermo-Alfredo Pulido-Estrada and Teke R. Apalata ()
Additional contact information
Urgent Tsuro: Department of Public Health, Faculty of Health Sciences, Walter Sisulu University, Mthatha 5100, South Africa
Kelechi E. Oladimeji: Department of Public Health, Faculty of Health Sciences, Walter Sisulu University, Mthatha 5100, South Africa
Guillermo-Alfredo Pulido-Estrada: Department of Public Health, Faculty of Health Sciences, Walter Sisulu University, Mthatha 5100, South Africa
Teke R. Apalata: Department of Laboratory Medicine and Pathology, Faculty of Health Sciences, Walter Sisulu University, Mthatha 5100, South Africa

IJERPH, 2022, vol. 19, issue 18, 1-14

Abstract: Background: Antiretroviral therapy has improved HIV patients’ quality of life and life expectancy. However, complications have emerged in the form of hypertension. In the rural Eastern Cape, there is minimal information about HIV-infected people. The current study intended to evaluate the factors associated with hypertension in HIV-infected individuals receiving antiretroviral therapy in rural areas of South Africa’s Eastern Cape. Methods: For this cohort study, HIV-positive people taking antiretroviral therapy aged 15 and up were recruited at random from several rural locations in the Eastern Cape. Using Cox univariate and multivariate analyses, the key predictors of hypertension were found. Results: Of the total participants (n = 361), 53% of individuals had hypertension. In the Cox multivariate model, patients that had hypertension heredity, BMI ≥ 25 kg/m 2 , eGFR < 60 mL/min/1.73 m 2 , advanced and severe CD4 counts, 1TFE and 1T3E regimens, and the male gender were found to be at greater risk of hypertension. Conclusions: The findings of this study indicate that hypertension is a prevalent concern among HIV patients receiving antiretroviral therapy. HIV patients should have their blood pressure checked regularly, and they should be screened for high blood pressure and given treatment for it.

Keywords: anti-retroviral therapy; HIV/AIDS; hypertension prevalence; hypertension risk factors; hypertension treatment (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/19/18/11196/pdf (application/pdf)
https://www.mdpi.com/1660-4601/19/18/11196/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:19:y:2022:i:18:p:11196-:d:908239

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().