Price and Prejudice? The Value of Chimeric Antigen Receptor (CAR) T-Cell Therapy

Gyeyoung Choi, Gyeongseon Shin and SeungJin Bae ()
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Gyeyoung Choi: College of Pharmacy, Ewha Womans University, Seoul 03760, Korea
Gyeongseon Shin: College of Pharmacy, Ewha Womans University, Seoul 03760, Korea
SeungJin Bae: College of Pharmacy, Ewha Womans University, Seoul 03760, Korea

IJERPH, 2022, vol. 19, issue 19, 1-6

Abstract: Although chimeric antigen receptor (CAR) T-cell therapy has shown a high response rate in lymphoma patients, its cost-effectiveness is controversial due to the high price and uncertainty of the clinical evidence. In addition to the high acquisition cost of CAR T-cell therapy, procedure and facility cost increase the financial burden considering the frequency of adverse events such as cytokine release syndrome. In clinical research, relatively short follow-up periods were used compared to traditional cancer agents. In addition, head-to-head comparative effectiveness data are unavailable, which is an important factor when evaluating the cost-effectiveness of a new treatment. Additional evidence that will compensate for the uncertainty of existing clinical data is needed for full evaluation of long-term efficacy, safety, and comparative effectiveness.

Keywords: chimeric antigen receptor T-cell therapy; CAR T-cell; economic evaluation; value (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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