Effects of a Resistance Training Protocol on Physical Performance, Body Composition, Bone Metabolism, and Systemic Homeostasis in Patients Diagnosed with Parkinson’s Disease: A Pilot Study

Alessandra Amato, Sara Baldassano (), Sonya Vasto, Giuseppe Schirò, Chiara Davì, Patrik Drid, Felipe Augusto Dos Santos Mendes, Rosalia Caldarella, Marco D’Amelio and Patrizia Proia ()
Additional contact information
Alessandra Amato: Sport and Exercise Sciences Research Unit, Department of Psychological, Pedagogical and Educational Sciences, University of Palermo, 90128 Palermo, Italy
Sara Baldassano: Department of Biological Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90128 Palermo, Italy
Sonya Vasto: Department of Biological Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90128 Palermo, Italy
Giuseppe Schirò: Department of Biomedicine, Neurosciences and Advanced Diagnostics (Bi.N.D.), University of Palermo, 90127 Palermo, Italy
Chiara Davì: Department of Biomedicine, Neurosciences and Advanced Diagnostics (Bi.N.D.), University of Palermo, 90127 Palermo, Italy
Patrik Drid: Faculty of Sport and Physical Education, University of Novi Sad, 21000 Novi Sad, Serbia
Felipe Augusto Dos Santos Mendes: Graduate Program in Rehabilitation Sciences, University of Brasília, Brasília 72220-275, Brazil
Rosalia Caldarella: Department of Laboratory Medicine, “P. Giaccone” University Hospital, 90127 Palermo, Italy
Marco D’Amelio: Department of Biomedicine, Neurosciences and Advanced Diagnostics (Bi.N.D.), University of Palermo, 90127 Palermo, Italy
Patrizia Proia: Sport and Exercise Sciences Research Unit, Department of Psychological, Pedagogical and Educational Sciences, University of Palermo, 90128 Palermo, Italy

IJERPH, 2022, vol. 19, issue 20, 1-17

Abstract: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor impairments and it is correlated with loss of bone mineral density. This study aimed to analyze the effects of resistance training on bone metabolism, systemic homeostasis, body composition, and physical performance in people with PD. Thirteen subjects (age 64.83 ± 5.70) with PD diagnosis were recruited. Participants performed neuromuscular tests, body composition assessment, and blood sample analysis at baseline, and after an 11 weeks-training period. Each training session lasted 90 min, three times a week. The participants had significant improvements in the timed up and go ( p < 0.01), sit to stand ( p < 0.01), dominant peg-board ( p < 0.05), dominant foot-reaction time ( p < 0.01), and functional reach tests ( p < 0.05). They showed better pressure foot distributions in the left forefoot ( p < 0.05) and hindfoot ( p < 0.05) and increased cervical right lateral bending angle ( p < 0.05). The protocol affects bone metabolism markers osteocalcin ( p < 0.05), calcium ( p < 0.01), PTH ( p < 0.01), the C-terminal telopeptide (CTX) ( p < 0.01), and vitamin D ( p < 0.05). Eleven weeks of resistance training improved manual dexterity, static and dynamic balance, reaction time, cervical ROM, and reduced bone loss in people with PD.

Keywords: physical activity; neurodegenerative disease; resistance training; bone resorption; osteogenesis; osteoporosis; Parkinson’s disease (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (4)

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