Effects of Grape Seed Extract Supplementation on Endothelial Function and Endurance Performance in Basketball Players

Hosung Nho () and Kyung-Ae Kim
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Hosung Nho: Department of Liberal Arts and Science, Suwon Women’s University, Onjeong Street 72, Gweonseon-gu, Suwon-si 16632, Korea
Kyung-Ae Kim: Human IT Solution, Gogum Building 1F, 2F, Banpo-daero, 55, Seocho-gu, Seoul 06670, Korea

IJERPH, 2022, vol. 19, issue 21, 1-8

Abstract: While dietary polyphenols supplements can improve endothelial function and blood flow to exercise, the effects of chronic supplementation with grape seed extract (GSE) containing a high dose of polyphenols on endurance performance are not known. Accordingly, in 12 elite athletes, we compared the effects of both GSE and placebo (PL) on submaximal VO 2 , time to exhaustion performance, and endothelial function during progressive cycling exercise for 14 days. Endothelial function was evaluated from the brachial artery via flow-mediated dilation (FMD). Compared to PL, GSE decreased submaximal VO 2 at 80% and 120% of VO 2peak and increased the time to exhaustion ( p < 0.05). GSE also resulted in FMD-induced increase in brachial artery diameter (14.4 ± 5.2% vs. 17.6 ± 4.5%, p = 0.035). We demonstrated that chronic supplementation with GSE improved endurance performance and these effects may partially be due to vasodilation in active skeletal muscle mediated by enhanced endothelial function. Thus, our results suggest that GSE appears to be an ergogenic nutraceutical that can improve exercise performance in elite athletes.

Keywords: grape seed extract; oxygen consumption; endurance performance; endothelial function; basketball players (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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