Biopsychosocial Correlates of Quality of Life in Multiple Sclerosis Patients

Ana Rita Batista, Susana Silva (), Leonor Lencastre and Marina Prista Guerra
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Ana Rita Batista: Center for Psychology at University of Porto (CPUP), Faculty of Psychology and Education Sciences, University of Porto, 4200-135 Porto, Portugal
Susana Silva: Center for Psychology at University of Porto (CPUP), Faculty of Psychology and Education Sciences, University of Porto, 4200-135 Porto, Portugal
Leonor Lencastre: Center for Psychology at University of Porto (CPUP), Faculty of Psychology and Education Sciences, University of Porto, 4200-135 Porto, Portugal
Marina Prista Guerra: Center for Psychology at University of Porto (CPUP), Faculty of Psychology and Education Sciences, University of Porto, 4200-135 Porto, Portugal

IJERPH, 2022, vol. 19, issue 21, 1-13

Abstract: Multiple sclerosis (MS) is a demyelinating chronic disease that has had increasing prevalence over the last years. We have investigated whether the perceived quality of life is reduced in multiple sclerosis patients compared to control participants with a cross-sectional approach, and how it relates to sociodemographic, clinical, and psychosocial variables in MS with multiple regression. To that end, a group of MS patients ( n = 50) and a control group ( n = 50) that was matched for age and education level filled in the WHOQOL-BREF (perceived quality of life across four domains) and a sociodemographic questionnaire. The participants in the MS group also filled in a clinical questionnaire and three instruments measuring psychosocial variables (the DASS-21 for depression, anxiety, and stress, the Brief-COPE for coping skills, and the Meaning in Life Scale). The results showed that the perceived quality of life was lower in the MS group than in the control group. Multiple regression models incorporating the variables that showed significant correlations with the quality of life indicated that age, professional status, recovery from relapses, depression, active coping, and meaning in life predicted at least one domain of the quality of life. Meaning in life predicted the quality of life in all four of the domains. Although the quality of life in MS is linked to multiple biopsychosocial variables, meaning in life seems crucial.

Keywords: multiple sclerosis; quality of life; biopsychosocial; meaning in life (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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