Mediterranean Diet Interventions for Depressive Symptoms in Adults with Depressive Disorders: A Protocol for a Systematic Review and Meta-Analysis

Bruno Bizzozero-Peroni, Andrés Godoy-Cumillaf (), Rubén Fernández-Rodríguez, Eva Rodríguez-Gutiérrez, Estela Jiménez-López, Frano Giakoni-Ramírez, Daniel Duclos-Bastías and Arthur Eumann Mesas
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Bruno Bizzozero-Peroni: Health and Social Research Center, Universidad de Castilla-La Mancha, 16071 Cuenca, Spain
Andrés Godoy-Cumillaf: Grupo de Investigación en Educación Física, Salud y Calidad de Vida, Facultad de Educación, Universidad Autónoma de Chile, Temuco 4780000, Chile
Rubén Fernández-Rodríguez: Health and Social Research Center, Universidad de Castilla-La Mancha, 16071 Cuenca, Spain
Eva Rodríguez-Gutiérrez: Health and Social Research Center, Universidad de Castilla-La Mancha, 16071 Cuenca, Spain
Estela Jiménez-López: Health and Social Research Center, Universidad de Castilla-La Mancha, 16071 Cuenca, Spain
Frano Giakoni-Ramírez: Faculty of Education and Social Sciences, Universidad Andres Bello, Las Condes, Santiago 7550000, Chile
Daniel Duclos-Bastías: Escuela de Educación Física, Pontificia Universidad Católica de Valparaíso, Valparaíso 2340000, Chile
Arthur Eumann Mesas: Health and Social Research Center, Universidad de Castilla-La Mancha, 16071 Cuenca, Spain

IJERPH, 2022, vol. 19, issue 21, 1-10

Abstract: The associations between Mediterranean diet (MD) adherence and depression levels have been synthesized from observational studies. However, a systematic review with meta-analysis including randomized controlled trials (RCTs) on this relationship in adults with depressive disorders remains lacking. This protocol was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analysis for Protocols statement. MEDLINE (PubMed), Cochrane CENTRAL, PsycINFO, Scopus, and Web of Science databases will be systematically searched to identify studies published from database inception up to 30 September 2022. The inclusion criteria will comprise RCTs reporting pre-post changes in depression status (symptoms or remission) after a MD intervention compared to a control condition in adults over 18 years with depressive disorders. Pooled effect sizes and 95% confidence intervals will be calculated using the DerSimonian random-effects model. This study protocol determines the methodological approach for the systematic review and meta-analysis that will summarize the available evidence on the efficacy of MD interventions on depressive symptoms in adults with depressive disorders. The findings from this review may have implications for public mental health programs. The results will be disseminated through peer-reviewed publication, conference presentation, and infographics. No ethical approval will be required since only published data will be used. PROSPERO registration number: CRD42022341895.

Keywords: adulthood; healthy diet; Mediterranean foods; depression; study protocol; systematic review (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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