Efficacy of Different Types of Physical Activity Interventions on Exercise Capacity in Patients with Chronic Obstructive Pulmonary Disease (COPD): A Network Meta-Analysis

Susana Priego-Jiménez, Ana Torres-Costoso, María José Guzmán-Pavón, Patricia Lorenzo-García, María Isabel Lucerón-Lucas-Torres () and Celia Álvarez-Bueno
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Susana Priego-Jiménez: Hospital Virgen de la Luz, 16002 Cuenca, Spain
Ana Torres-Costoso: Health and Social Research Center, Universidad de Castilla La Mancha, 16071 Cuenca, Spain
María José Guzmán-Pavón: Health and Social Research Center, Universidad de Castilla La Mancha, 16071 Cuenca, Spain
Patricia Lorenzo-García: Health and Social Research Center, Universidad de Castilla La Mancha, 16071 Cuenca, Spain
María Isabel Lucerón-Lucas-Torres: Health and Social Research Center, Universidad de Castilla La Mancha, 16071 Cuenca, Spain
Celia Álvarez-Bueno: Health and Social Research Center, Universidad de Castilla La Mancha, 16071 Cuenca, Spain

IJERPH, 2022, vol. 19, issue 21, 1-24

Abstract: Aim: A network meta-analysis (NMA) was performed to determine the effects on the exercise capacity, measured by the 6 MWT, of patients with COPD of (i) different physical activity interventions and (ii) supervised or unsupervised programs. Methods: A literature search was carried out from inception to April 2022. Randomized controlled trials of the effectiveness of physical activity on exercise capacity in patients with COPD were included. The risk of bias was assessed using the Cochrane Risk of Bias (RoB 2.0) tool, and the Grading of Recommendations, Assessment, Development, and Evaluation tool (GRADE) was used to assess the quality of the evidence. A pairwise meta-analysis for direct and indirect effects was carried out. Results: A total of 41 studies were included in this NMA. The highest effects were for urban training pulmonary rehabilitation (PR) programs (ES, 1.50; 95% CI: 0.46 and 2.55) versus the control group. For supervised and unsupervised PR and home-based PR programs, the highest effects were found for supervised PR (ES, 0.85; 95% CI: 0.46 to 1.23) versus the control group. Conclusions: PR implemented with urban circuit training should be considered the most effective strategy to improve exercise capacity in patients with COPD. Supervision of the programs improves exercise capacity.

Keywords: COPD; pulmonary rehabilitation; systematic review; meta-analysis; exercise capacity; active mind-body movements therapies; physical activity; 6MWT (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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