Implementation and Effectiveness of a Pharmacotherapeutic Follow-Up Service for People with Tuberculosis in Primary Healthcare

Célio Rezende Lara-Júnior, Ana Emília de Oliveira Ahouagi, Isabela Vaz Leite Pinto, Debora Gontijo Braga, Thiago Rabelo Andrade, Djenane Ramalho- de-Oliveira and Mariana Martins Gonzaga do Nascimento ()
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Célio Rezende Lara-Júnior: Center for Pharmaceutical Care Studies, College of Pharmacy, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil
Ana Emília de Oliveira Ahouagi: Belo Horizonte Municipality, Belo Horizonte 30130-003, MG, Brazil
Isabela Vaz Leite Pinto: Belo Horizonte Municipality, Belo Horizonte 30130-003, MG, Brazil
Debora Gontijo Braga: Belo Horizonte Municipality, Belo Horizonte 30130-003, MG, Brazil
Thiago Rabelo Andrade: Belo Horizonte Municipality, Belo Horizonte 30130-003, MG, Brazil
Djenane Ramalho- de-Oliveira: Center for Pharmaceutical Care Studies, College of Pharmacy, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil
Mariana Martins Gonzaga do Nascimento: Center for Pharmaceutical Care Studies, College of Pharmacy, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil

IJERPH, 2022, vol. 19, issue 21, 1-9

Abstract: Tuberculosis (TB) is a disease of great relevance, responsible for 1.5 million deaths worldwide. Therefore, actions to control TB are necessary, and pharmacists may play an important role, especially in primary healthcare (PHC), where the diagnosis and management of this infection occurs. In a large Brazilian city, pharmacotherapeutic follow-up in PHC has been offered by pharmacists to people with TB since 2018. The objective of this study was to evaluate the implementation and effectiveness of this service though a longitudinal type 1 effectiveness–implementation hybrid study. Data were collected from January 2018 to February 2020 in the pharmaceutical services system. The service indicators were described and effectiveness was evaluated using Poisson regression analysis to compare the incidence of cure among patients using and not using the service. The service was performed in 148 PHC units by 82 pharmacists. Of the total of 1076 treatments, 721 were followed up by pharmacists, and TB was cured more frequently in these cases (90.4% attended vs. 73.5% unattended). The adjusted hazard ratio of cure among patients enrolled in the pharmacotherapeutic follow-up service was 2.71 (2.04–3.61; p < 0.001). Pharmacotherapeutic follow-up for people with TB significantly increased the incidence of cure and should be encouraged.

Keywords: tuberculosis; primary healthcare; pharmaceutical services; evidence-based pharmacy practice (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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