The Medication Experience of TB/HIV Coinfected Patients: Qualitative Study

Natália Helena de Resende (), Ursula Carolina de Morais Martins, Djenane Ramalho- de-Oliveira, Dirce Inês da Silva, Silvana Spíndola de Miranda, Adriano Max Moreira Reis, Wânia da Silva Carvalho and Simone de Araújo Medina Mendonça
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Natália Helena de Resende: Graduate Program in Medicines and Pharmaceutical Assistance, College of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil
Ursula Carolina de Morais Martins: Graduate Program in Medicines and Pharmaceutical Assistance, College of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil
Djenane Ramalho- de-Oliveira: Graduate Program in Medicines and Pharmaceutical Assistance, College of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil
Dirce Inês da Silva: Hospital Foundation of the State of Minas Gerais/Eduardo de Menezes Hospital, Belo Horizonte 30622-020, Brazil
Silvana Spíndola de Miranda: Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Brazil
Adriano Max Moreira Reis: Graduate Program in Medicines and Pharmaceutical Assistance, College of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil
Wânia da Silva Carvalho: Graduate Program in Medicines and Pharmaceutical Assistance, College of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil
Simone de Araújo Medina Mendonça: Graduate Program in Medicines and Pharmaceutical Assistance, College of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil

IJERPH, 2022, vol. 19, issue 22, 1-11

Abstract: Tuberculosis (TB) and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) pharmacotherapy and the stigma related to both diseases are complex. The patients’ subjective experiences with diseases and medications are of utmost importance in pharmaceutical care practice. This study aimed to understand the subjective medication experience of TB and HIV/AIDS coinfected patients. The study was based on descriptive research of a qualitative and quantitative nature using data collected during pharmaceutical care appointments and from medical records from September 2015 to December 2016 at a tertiary infectious diseases referral hospital in Southeastern Brazil. Data from 81 patients were analyzed. Regarding patient subjective medication experience, the following responses to the quantitative questionnaire were most frequent: preference for a route of administration (12.4%) and for non-pharmacological therapy (50.6%); concerns about price (11.1%) and adverse effects (18.5%); and association of a worsening of their health status with a change in medication dosage (23.5%). In the thematic analysis, adversity and socially constructed aspects were more prominent. Resolvability, associated with the patient’s understanding of relief from signs and symptoms and health recovery, was observed; however, feelings of ambivalence permeated the other aspects, hence leading to treatment abandonment. The evaluation of patient medication experience can be a path to understanding and intervening in the phenomenon of treatment abandonment among TB and HIV/AIDS coinfected individuals.

Keywords: HIV/AIDS; tuberculosis; medication experience; medication use; Brazil (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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