Circadian Variations and Associated Factors in Patients with Ischaemic Heart Disease

Marisa Estarlich, Carmen Tolsa, Isabel Trapero () and Cristina Buigues
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Marisa Estarlich: Department of Nursing, University of Valencia, 46010 Valencia, Spain
Carmen Tolsa: Department of Nursing, University of Valencia, 46010 Valencia, Spain
Isabel Trapero: Department of Nursing, University of Valencia, 46010 Valencia, Spain
Cristina Buigues: Department of Nursing, University of Valencia, 46010 Valencia, Spain

IJERPH, 2022, vol. 19, issue 23, 1-11

Abstract: Circadian rhythms have been identified in cardiovascular diseases, and cardiovascular risk factors can modify the circadian rhythm. The purpose of this study was to describe the onset of ischaemic heart disease symptomatology in relation to the date and time, the day of the week of presentation, the season, AMI location and severity and the level of influence of individual patient characteristics in a retrospective cross-sectional study involving 244 ischaemic heart disease patients from the intensive care unit of La Ribera Hospital (Spain). The onset of pain was more frequent in the morning, the season with the highest frequency of ischaemic events was winter, and the lowest incidence was during weekends. Regarding the severity of ischaemic heart disease, the circadian rhythm variables of weekdays vs. weekends and seasons did not show a significant association. The length of hospital stay was associated with the onset of pain in the afternoon. The onset of pain at night was associated with the subendocardial location of the infarction. In conclusion, living in a Mediterranean country, the Spanish population showed a circadian pattern of AMI, where the onset of pain has an influence on AMI location and on the length of hospital stay and is the same in patients with different individual risk factors.

Keywords: myocardial infarction; circadian rhythm; individual risk factors; AMI location; severity (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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