The Potential of Exerkines in Women’s COVID-19: A New Idea for a Better and More Accurate Understanding of the Mechanisms behind Physical Exercise

Katsuhiko Suzuki (), Amir Hossein Ahmadi Hekmatikar, Shadi Jalalian, Shaghayegh Abbasi, Elmira Ahmadi, Abdolreza Kazemi, Ruheea Taskin Ruhee and Kayvan Khoramipour ()
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Katsuhiko Suzuki: Faculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan
Amir Hossein Ahmadi Hekmatikar: Department of Physical Education and Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran 10600, Iran
Shadi Jalalian: Department of Physical Education and Sport Sciences, Science and Research Branch, Islamic Azad University, Tehran 10600, Iran
Shaghayegh Abbasi: Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Kharazmi University, Tehran 10600, Iran
Elmira Ahmadi: Department of Physical Education and Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran 10600, Iran
Abdolreza Kazemi: Department of Sports Science, Faculty of Literature and Humanities, Vali-e-Asr University, Rafsanjan 7718897111, Iran
Ruheea Taskin Ruhee: Future Innovation Institute, Waseda University, Shinjuku 162-0041, Japan
Kayvan Khoramipour: Neuroscience Research Center, Institute of Neuropharmacology, Department of Physiology, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman 7616914115, Iran

IJERPH, 2022, vol. 19, issue 23, 1-21

Abstract: The benefits of physical exercise are well-known, but there are still many questions regarding COVID-19. Chow et al.’s 2022 study, titled Exerkines and Disease, showed that a special focus on exerkines can help to better understand the underlying mechanisms of physical exercise and disease. Exerkines are a group of promising molecules that may underlie the beneficial effects of physical exercise in diseases. The idea of exerkines is to understand the effects of physical exercise on diseases better. Exerkines have a high potential for the treatment of diseases and, considering that, there is still no study of the importance of exerkines on the most dangerous disease in the world in recent years, COVID-19. This raises the fundamental question of whether exerkines have the potential to manage COVID-19. Most of the studies focused on the general changes in physical exercise in patients with COVID-19, both during the illness and after discharge from the hospital, and did not investigate the basic differences. A unique look at the management of COVID-19 by exerkines, especially in obese and overweight women who experience high severity of COVID-19 and whose recovery period is long after discharge from the hospital, can help to understand the basic mechanisms. In this review, we explore the potential of exerkines in COVID-19 by practicing physical exercise to provide compelling practice recommendations with new insights.

Keywords: coronavirus disease 2019 (COVID-19); exerkines; females; women health; physical exercise; physical activity; SARS-CoV-2 virus; resistance training; aerobic exercise; Omicron (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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