Psychological Implications to the Therapy of Systemic Lupus Erythematosus

Katarzyna Warchoł-Biedermann (), Ewa Mojs (), Dorota Sikorska, Przemysław Kotyla, Grażyna Teusz and Włodzimierz Samborski
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Katarzyna Warchoł-Biedermann: Department of Clinical Psychology, Poznan University of Medical Sciences, 60-812 Poznan, Poland
Ewa Mojs: Department of Clinical Psychology, Poznan University of Medical Sciences, 60-812 Poznan, Poland
Dorota Sikorska: Department of Rheumatology, Rehabilitation and Internal Diseases, Poznan University of Medical Sciences, 61-545 Poznan, Poland
Przemysław Kotyla: Department of Internal Medicine, Rheumatology and Clinical Immunology, Medical University of Silesia Katowice, 40-635 Katowice, Poland
Grażyna Teusz: Faculty of Educational Studies, Adam Mickiewicz University, 61-712 Poznan, Poland
Włodzimierz Samborski: Department of Rheumatology, Rehabilitation and Internal Diseases, Poznan University of Medical Sciences, 61-545 Poznan, Poland

IJERPH, 2022, vol. 19, issue 23, 1-19

Abstract: Systemic lupus erythematosus (SLE) is a chronic and multi-systemic autoimmune disease, which has a deleterious impact on patients’ psychological well-being. This paper aims to review the existing literature on empirical research on psychological outcomes of SLE and psychological interventions to improve well-being in SLE patients. A search of significant English language articles was conducted in PubMed, Medline, ScienceDirect, Scopus, and ResearchGate databases. Titles and abstracts were screened for the relevant terms, including “systemic lupus erythematosus”, “childhood-onset systemic lupus erythematosus”, “juvenile systemic lupus erythematosus”, “lupus nephritis”, and their respective synonyms along with “depression”, “anxiety”, “fatigue”, “medical adherence”, “health-related quality of life”, “self-management” or “intervention”. The articles were evaluated by independent reviewers and the lists of eligible publications were compared whilst disagreements were settled by discussion. Of the 59 publications sought for retrieval, 35 papers were shortlisted based on predefined inclusion/exclusion criteria. They were classified according to their content and the methodology applied. Research topics including “anxiety and depression in SLE” and “self-management interventions for SLE patients” were identified and are presented in this review. As the prognosis and life expectancy of SLE patients are improving, further research on the psychological outcomes of SLE and the evidence-based psychological interventions to improve patients’ well-being are justified.

Keywords: medication adherence; surveys and questionnaires; lupus nephritis; rheumatology (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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