Comparative Biomonitoring of Arsenic Exposure in Mothers and Their Neonates in Comarca Lagunera, Mexico

José Javier García Salcedo, Taehyun Roh, Lydia Enith Nava Rivera, Nadia Denys Betancourt Martínez, Pilar Carranza Rosales, María Francisco San Miguel Salazar, Mario Alberto Rivera Guillén, Luis Benjamín Serrano Gallardo, María Soñadora Niño Castañeda, Nacny Elena Guzmán Delgado, Jair Millán Orozco, Natalia Ortega Morales and Javier Morán Martínez ()
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José Javier García Salcedo: Departamento de Bioquímica y Farmacología, Centro de Investigaciones Biomédicas, Facultad de Medicina, Universidad Autónoma de Coahuila Torreón, Torreón 27000, Mexico
Taehyun Roh: Department of Epidemiology and Biostatistics, School of Public Health, Texas A&M University, College Station, TX 77843, USA
Lydia Enith Nava Rivera: Departamento de Biología Celular y Ultraestructura, Centro de Investigaciones Biomédicas, Facultad de Medicina, Universidad Autónoma de Coahuila Torreón, Torreón 27000, Mexico
Nadia Denys Betancourt Martínez: Departamento de Biología Celular y Ultraestructura, Centro de Investigaciones Biomédicas, Facultad de Medicina, Universidad Autónoma de Coahuila Torreón, Torreón 27000, Mexico
Pilar Carranza Rosales: Centro de Investigaciones Biomédicas del Noreste, Instituto Mexicano del Seguro Social, Monterrey 64000, Mexico
María Francisco San Miguel Salazar: Departamento de Bioquímica y Farmacología, Centro de Investigaciones Biomédicas, Facultad de Medicina, Universidad Autónoma de Coahuila Torreón, Torreón 27000, Mexico
Mario Alberto Rivera Guillén: Departamento de Bioquímica y Farmacología, Centro de Investigaciones Biomédicas, Facultad de Medicina, Universidad Autónoma de Coahuila Torreón, Torreón 27000, Mexico
Luis Benjamín Serrano Gallardo: Departamento de Bioquímica y Farmacología, Centro de Investigaciones Biomédicas, Facultad de Medicina, Universidad Autónoma de Coahuila Torreón, Torreón 27000, Mexico
María Soñadora Niño Castañeda: Departamento de Biología Celular y Ultraestructura, Centro de Investigaciones Biomédicas, Facultad de Medicina, Universidad Autónoma de Coahuila Torreón, Torreón 27000, Mexico
Nacny Elena Guzmán Delgado: División de Investigaciones en Salud, Unidad Médica de Alta Especialidad, Hospital de Cardiología #34, Instituto Mexicano del Seguro Social, Monterrey 64000, Mexico
Jair Millán Orozco: Unidad Laguna, Universidad Autónoma Agraria Antonio Narro, Raúl López Sánchez, Torreon 27000, Mexico
Natalia Ortega Morales: División de Investigaciones en Salud, Unidad Médica de Alta Especialidad, Hospital de Cardiología #34, Instituto Mexicano del Seguro Social, Monterrey 64000, Mexico
Javier Morán Martínez: Departamento de Biología Celular y Ultraestructura, Centro de Investigaciones Biomédicas, Facultad de Medicina, Universidad Autónoma de Coahuila Torreón, Torreón 27000, Mexico

IJERPH, 2022, vol. 19, issue 23, 1-10

Abstract: Multiple comorbidities related to arsenic exposure through drinking water continue to be public problems worldwide, principally in chronically exposed populations, such as those in the Comarca Lagunera (CL), Mexico. In addition, this relationship could be exacerbated by an early life exposure through the placenta and later through breast milk. This study conducted a comparative analysis of arsenic levels in multiple biological samples from pregnant women and their neonates in the CL and the comparison region, Saltillo. Total arsenic levels in placenta, breast milk, blood, and urine were measured in pregnant women and their neonates from rural areas of seven municipalities of the CL using atomic absorption spectrophotometry with hydride generation methodology. The average concentrations of tAs in drinking water were 47.7 µg/L and 0.05 µg/L in the exposed and non-exposed areas, respectively. Mean levels of tAs were 7.80 µg/kg, 77.04 µg/g-Cr, and 4.30 µg/L in placenta, blood, urine, and breast milk, respectively, in mothers, and 107.92 µg/g-Cr in neonates in the exposed group, which were significantly higher than those in the non-exposed area. High levels of urinary arsenic in neonates were maintained 4 days after birth, demonstrating an early arsenic exposure route through the placenta and breast milk. In addition, our study suggested that breastfeeding may reduce arsenic exposure in infants in arsenic-contaminated areas. Further studies are necessary to follow up on comorbidities later in life in neonates and to provide interventions in this region.

Keywords: arsenic; drinking water; biomonitoring; breast milk; neonates; pregnancy (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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