Post-Exposure Prophylaxis and Methamphetamine Use among Young Sexual Minority Men: The P18 Cohort Study

Elizabeth Kaplun, Richard J. Martino, Kristen D. Krause, Michael Briganti, Paul A. D’Avanzo and Perry N. Halkitis
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Elizabeth Kaplun: Center for Health, Identity, Behavior, and Prevention Studies, Rutgers School of Public Health, Newark, NJ 07102, USA
Richard J. Martino: Center for Health, Identity, Behavior, and Prevention Studies, Rutgers School of Public Health, Newark, NJ 07102, USA
Kristen D. Krause: Center for Health, Identity, Behavior, and Prevention Studies, Rutgers School of Public Health, Newark, NJ 07102, USA
Michael Briganti: Center for Health, Identity, Behavior, and Prevention Studies, Rutgers School of Public Health, Newark, NJ 07102, USA
Paul A. D’Avanzo: Center for Health, Identity, Behavior, and Prevention Studies, Rutgers School of Public Health, Newark, NJ 07102, USA
Perry N. Halkitis: Center for Health, Identity, Behavior, and Prevention Studies, Rutgers School of Public Health, Newark, NJ 07102, USA

IJERPH, 2022, vol. 19, issue 2, 1-12

Abstract: Methamphetamine use is associated with increased risk of HIV infection among young sexual minority men (SMM). Post-exposure prophylaxis (PEP) is an effective strategy for individuals who are exposed to HIV, but there is limited research about PEP use among young SMM and its relationship with methamphetamine use. This study analyzes the association between ever PEP use and recent methamphetamine use among young SMM in New York City, using cross-sectional data from the P18 Cohort Study ( n = 429). Multivariable logistic regression models were used to assess the association between methamphetamine use and ever PEP use. Compared with those who had not used methamphetamine in the last 6 months, young SMM who did use methamphetamine were significantly more likely to have ever used PEP (AOR = 6.07, 95% CI: 2.10–16.86). Young SMM who had ever used PrEP had 16 times higher odds of ever using PEP (AOR = 16, 95% CI: 7.41–35.95). Those who completed bachelor’s degrees were 61% less likely to have ever used PEP (AOR = 0.39, 95% CI: 0.17–0.88). These data suggest that methamphetamine use could increase the risk of HIV infection, highlighting the critical need to target interventions for young SMM who use methamphetamine and are more likely to engage in unprotected intercourse.

Keywords: substance use; sexual health; sexual minority; gender minority; racial and ethnic minority; syndemic theory (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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