Risk of Mortality in Association with Pregnancy in Women Following Motor Vehicle Crashes: A Systematic Review and Meta-Analysis

Ya-Hui Chang, Ya-Yun Cheng, Wen-Hsuan Hou, Yu-Wen Chien, Chiung-Hsin Chang, Ping-Ling Chen, Tsung-Hsueh Lu, Lucia Yovita Hendrati, Chung-Yi Li and Ning-Ping Foo
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Ya-Hui Chang: Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan
Ya-Yun Cheng: Department of Environmental and Occupational Health, National Cheng Kung University, Tainan 70101, Taiwan
Wen-Hsuan Hou: Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei 11031, Taiwan
Yu-Wen Chien: Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan
Chiung-Hsin Chang: Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan
Ping-Ling Chen: Graduate Institute of Injury Prevention and Control, College of Public Health, Taipei Medical University, Taipei 11031, Taiwan
Tsung-Hsueh Lu: Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan
Lucia Yovita Hendrati: Department of Epidemiology, Biostatistics, Population Studies and Health Promotion, Faculty of Public Health, University of Airlangga, Surabaya 60115, Indonesia
Chung-Yi Li: Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan
Ning-Ping Foo: Department of Emergency Medicine, An Nan Hospital, China Medical University, Tainan 70965, Taiwan

IJERPH, 2022, vol. 19, issue 2, 1-10

Abstract: The aim of the study was to provide a systematic review and meta-analysis of studies examining the association between mortality risk and motor vehicle crashes (MVCs) in pregnant women compared with nonpregnant women. We used relevant MeSH terms to identify epidemiological studies of mortality risk in relation to MVCs from PubMed, Embase, and MEDLINE databases. The Newcastle–Ottawa Scale (NOS) was used for quality assessment. For comparison of mortality from MVCs between pregnant and nonpregnant women, the pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated using a random effects model. The eight studies selected met all inclusion criteria. These studies included 14,120 injured victims who were pregnant at the time of the incident and 207,935 victims who were not pregnant. Compared with nonpregnant women, pregnant women had a moderate but insignificant decrease in mortality risk (pooled OR = 0.68, 95% CI = 0.38–1.22, I 2 = 88.71%). Subgroup analysis revealed that the pooled OR significantly increased at 1.64 (95% CI = 1.16–2.33, I 2 < 0.01%) for two studies with a similar difference in the mean injury severity score (ISS) between pregnant and nonpregnant women. Future studies should further explore the risk factors associated with MVCs in pregnant women to reduce maternal mortality.

Keywords: injury severity score; mortality; traffic accident; pregnancy (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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