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Predictors of the Development of Mental Disorders in Hospitalized COVID-19 Patients without Previous Psychiatric History: A Single-Center Retrospective Study in South Korea

Jangrae Kim, Yae Eun Seo, Ho Kyung Sung, Hye Yoon Park, Myung Hwa Han and So Hee Lee
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Jangrae Kim: Department of Psychiatry, National Medical Center, Eulji-ro 245, Jung-gu, Seoul 04564, Korea
Yae Eun Seo: Department of Psychiatry, National Medical Center, Eulji-ro 245, Jung-gu, Seoul 04564, Korea
Ho Kyung Sung: Institute for Public Healthcare, National Medical Center, Eulji-ro 245, Jung-gu, Seoul 04564, Korea
Hye Yoon Park: Department of Psychiatry, Seoul National University Hospital, Daehak-ro 101, Jongno-gu, Seoul 03080, Korea
Myung Hwa Han: Department of Psychiatry, National Medical Center, Eulji-ro 245, Jung-gu, Seoul 04564, Korea
So Hee Lee: Department of Psychiatry, National Medical Center, Eulji-ro 245, Jung-gu, Seoul 04564, Korea

IJERPH, 2022, vol. 19, issue 3, 1-11

Abstract: The objective of this study was to investigate the predictors for new-onset mental disorders among patients with mild to moderate COVID-19 illness during hospitalization. A retrospective cohort study was performed in patients with confirmed COVID-19 admitted to a nationally designated hospital between 1 February and 30 June 2020. Demographic, clinical, psychological assessments, and psychiatric outcomes were obtained from electronic medical record review. Multivariate logistic regression analysis was used to identify predictors of new-onset mental disorders. Among 185 patients, 130 had no history of mental disorders or cognitive impairment at the time of admission. Of 130 patients, 29 (22.3%) were newly diagnosed with mental disorders during hospitalization. The following factors were significantly associated with an increased risk of a psychiatric diagnosis: Charlson comorbidity index core ≥1 (adjusted odds ratio (aOR) = 5.115, 95% confidence interval (CI): 1.737–15.058), length of stay (aOR per 1-day increase = 1.067, 95% CI: 1.035–1.100), and self-reported depressive symptoms at the time of admission (aOR = 5.357, 95% CI: 1.745–16.444). The predictive accuracy of combining these risk factors was relatively high (area under curve = 0.851, 95% CI: 0.778–0.923). These potential risk factors could help to predict the new-onset mental disorder among hospitalized patients with COVID-19.

Keywords: COVID-19; mental disorder; cohort study; prognosis; Republic of Korea (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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