The Value of Clinical Frailty Scale (CFS) as a Prognostic Tool in Predicting Mortality in COVID-19—A Retrospective Cohort Study

Magdalena Jachymek, Aleksandra Cader, Michał Ptak, Wojciech Witkiewicz, Adam Grzegorz Szymański, Katarzyna Kotfis, Jarosław Kaźmierczak and Aleksandra Szylińska
Additional contact information
Magdalena Jachymek: Department of Cardiology, Pomeranian Medical University, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland
Aleksandra Cader: Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Powskańców Wielkopolskich 72, 70-111 Szczecin, Poland
Michał Ptak: Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Powskańców Wielkopolskich 72, 70-111 Szczecin, Poland
Wojciech Witkiewicz: Department of Cardiology, Pomeranian Medical University, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland
Adam Grzegorz Szymański: Department of Cardiology, Pomeranian Medical University, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland
Katarzyna Kotfis: Department Anesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland
Jarosław Kaźmierczak: Department of Cardiology, Pomeranian Medical University, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland
Aleksandra Szylińska: Department of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University in Szczecin, Żołnierska 54, 71-210 Szczecin, Poland

IJERPH, 2022, vol. 19, issue 3, 1-15

Abstract: Background: Due to the unpredictable nature of COVID-19, there is a need to identify patients at high risk of severe course of the disease and a higher mortality rate. Objective: This study aims to find the correlation between frailty and mortality in adult, hospitalized patients with COVID-19. Methods: Clinical records of 201 patients who suffered from COVID-19 and were hospitalized between October 2020 and February 2021 were retrospectively analyzed. Demographic, clinical, and biochemical data were collected. Patients were assessed using Clinical Frailty Scale (CFS) and were divided into three groups: CFS 1–3 fit; CFS 4–6 vulnerable and with mild to moderate frailty; CSF 7–9, severe frailty. The association between frailty and in-hospital mortality was the primary outcome. Results: Severe frailty or terminal illness was observed in 26 patients (12.94%) from a cohort of 201 patients. Those patients were older (median age 80.73, p < 0.001) and had more comorbidities. Frailty was also associated with higher requirement for oxygen supplementation, greater risk of in-hospital complications and worse biochemical laboratory results. An increase in CFS score also correlated with higher mortality (OR = 1.89, p < 0.001). The Conclusions: Clinical Frailty Scale (CFS) can be used as a potentially useful tool in predicting mortality in patients with COVID-19.

Keywords: clinical frailty scale; COVID-19; SARS-CoV-2; coronavirus; outcome; mortality (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/19/3/1104/pdf (application/pdf)
https://www.mdpi.com/1660-4601/19/3/1104/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:19:y:2022:i:3:p:1104-:d:728423

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().