Dental Implants in People with Osteogenesis Imperfecta: A Systematic Review

Ole Oelerich, Johannes Kleinheinz, Lauren Bohner, Vera Wiesmüller and Marcel Hanisch
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Ole Oelerich: Department for Prosthodontics and Biomaterials, University Hospital Münster, D-48149 Münster, Germany
Johannes Kleinheinz: Research Unit Rare Diseases with Orofacial Manifestations, Department of Cranio-Maxillofacial Surgery, University Hospital Münster, D-48149 Münster, Germany
Lauren Bohner: Research Unit Rare Diseases with Orofacial Manifestations, Department of Cranio-Maxillofacial Surgery, University Hospital Münster, D-48149 Münster, Germany
Vera Wiesmüller: Department of Operative and Prosthetic Dentistry, Medical University of Innsbruck, A-6020 Innsbruck, Austria
Marcel Hanisch: Research Unit Rare Diseases with Orofacial Manifestations, Department of Cranio-Maxillofacial Surgery, University Hospital Münster, D-48149 Münster, Germany

IJERPH, 2022, vol. 19, issue 3, 1-15

Abstract: The aim of this systematic review was to answer the question of whether patients with osteogenesis imperfecta can be prosthetically rehabilitated with dental implants. A protocol was prospectively registered in PROSPERO (CRD42021286368). The inclusion criteria were the presence of osteogenesis imperfecta and the use of implants for prosthetic restorations. Cases in which the inclusion criteria were not met were excluded. PubMed, Web of Science, and Scopus were last searched on 22 August 2021. Quality assessment was performed using the Methodological Quality and Synthesis of Case Series and Case Reports tool. The primary outcome was implant survival. Supporting data were analyzed descriptively. Twelve studies were included. Twenty-three patients received a total number of 116 implants, with 5.0 (±3.8) implants placed per patient. The implant survival rate was 94.0% with a mean follow-up of 59.1 months (±36.1). A limitation of this review was the relatively short follow-up time in some of the included studies; therefore, the survival rate may be overestimated. Nevertheless, the available data showed the loss of only seven implants, with two implants lost due to implant fractures not attributable to the patient. With the limitations of this review and based on the available data, dental implants have a high survival rate in patients with osteogenesis imperfecta. Therefore, dental implants may be a viable treatment option for replacing missing teeth. This research was not funded by external resources.

Keywords: dental implants; osteogenesis imperfecta; systematic review; rare disease (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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