‘Physio-EndEA’ Study: A Randomized, Parallel-Group Controlled Trial to Evaluate the Effect of a Supervised and Adapted Therapeutic Exercise Program to Improve Quality of Life in Symptomatic Women Diagnosed with Endometriosis

María del Mar Salinas-Asensio, Olga Ocón-Hernández, Antonio Mundo-López, Carolina Fernández-Lao, Francisco M. Peinado, Carmen Padilla-Vinuesa, Francisco Álvarez-Salvago, Paula Postigo-Martín, Mario Lozano-Lozano, Ana Lara-Ramos, Manuel Arroyo-Morales, Irene Cantarero-Villanueva and Francisco Artacho-Cordón
Additional contact information
María del Mar Salinas-Asensio: Department of Physiotherapy, University of Granada, E-18016 Granada, Spain
Olga Ocón-Hernández: Biohealth Research Institute in Granada (ibs.GRANADA), E-18012 Granada, Spain
Antonio Mundo-López: Clinic Psychology Center Alarcón (CPCA), E-18004 Granada, Spain
Carolina Fernández-Lao: Department of Physiotherapy, University of Granada, E-18016 Granada, Spain
Francisco M. Peinado: Biohealth Research Institute in Granada (ibs.GRANADA), E-18012 Granada, Spain
Carmen Padilla-Vinuesa: Biohealth Research Institute in Granada (ibs.GRANADA), E-18012 Granada, Spain
Francisco Álvarez-Salvago: Department of Physiotherapy, European University of Valencia, E-46010 Valencia, Spain
Paula Postigo-Martín: Department of Physiotherapy, University of Granada, E-18016 Granada, Spain
Mario Lozano-Lozano: Department of Physiotherapy, University of Granada, E-18016 Granada, Spain
Ana Lara-Ramos: Gynaecology and Obstetrics Unit, ‘Virgen de las Nieves’ University Hospital, E-18012 Granada, Spain
Manuel Arroyo-Morales: Department of Physiotherapy, University of Granada, E-18016 Granada, Spain
Irene Cantarero-Villanueva: Department of Physiotherapy, University of Granada, E-18016 Granada, Spain
Francisco Artacho-Cordón: Biohealth Research Institute in Granada (ibs.GRANADA), E-18012 Granada, Spain

IJERPH, 2022, vol. 19, issue 3, 1-16

Abstract: Aim: The ‘Physio-EndEA’ study aims to explore the potential benefits of a therapeutic exercise program (focused on lumbopelvic stabilization and tolerance to exertion) on the health-related quality of life (HRQoL) of symptomatic endometriosis women. Design: The present study will use a parallel-group randomized controlled trial design. Methods: A total of 22 symptomatic endometriosis women will be randomized 1:1 to the Physio-EndEA or usual care groups. The ‘Physio-EndEA’ program will consist of a one-week lumbopelvic stabilization learning phase followed by an eight-week phase of stretching, aerobic and resistance exercises focused on the lumbopelvic area that will be sequentially instructed and supervised by a trained physiotherapist (with volume and intensity progression) and adapted daily to the potential of each participant. The primary outcome measure is HRQoL. The secondary outcome measures included clinician-reported outcomes (pressure pain thresholds, muscle thickness and strength, flexibility, body balance and cardiorespiratory fitness) and patient-reported outcomes (pain intensity, physical fitness, chronic fatigue, sexual function, gastrointestinal function and sleep quality). Discussion: Findings of this study will help to identify cost-effective non-pharmacological options (such as this exercise-based intervention) that may contribute to the improvement of HRQoL in symptomatic endometriosis women.

Keywords: endometriosis; physiotherapy; therapeutic exercise; quality of life; motor control; pain (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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