Evaluating the Oral-Health-Related Quality of Life of Oral Submucous Fibrosis Patients before and after Treatment Using the OHIP-14 Tool

Abdul Bari Memon, Aneela Atta Ur Rahman, Kashif Ali Channar, Muhammad Sohail Zafar and Naresh Kumar
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Abdul Bari Memon: Medical Research Centre, Liaquat University of Medical and Health Sciences, Jamshoro 76090, Pakistan
Aneela Atta Ur Rahman: Medical Research Centre, Liaquat University of Medical and Health Sciences, Jamshoro 76090, Pakistan
Kashif Ali Channar: Department of Oral and Maxillofacial Surgery, Institute of Dentistry, Liaquat University of Medical and Health Sciences, Jamshoro 76090, Pakistan
Muhammad Sohail Zafar: Department of Restorative Dentistry, College of Dentistry, Taibah University, Al Madinah, Al Munawwarah 41311, Saudi Arabia
Naresh Kumar: Medical Research Centre, Liaquat University of Medical and Health Sciences, Jamshoro 76090, Pakistan

IJERPH, 2022, vol. 19, issue 3, 1-10

Abstract: The objective of the present study was to assess the oral-health-related quality of life (OHRQoL) of oral submucous fibrosis (OSMF) patients before and after standard treatment. A convenient sampling technique was used to recruit the clinically diagnosed patients of OSMF (n = 130). Based on the medical treatment, the patients were randomly divided into two study groups (group A and B). The group A patients received submucosal intralesional injections of dexamethasone (2 mL; 4 gm/mL), while group B patients received hyaluronidase (1500 IU). Both the group A and B patients received respective medical therapy biweekly for a period of five weeks. At the follow up visit (6 months), the impact of treatment on OHRQoL was assessed using the Oral Health Impact Profile-14 (OHIP-14). Data were analyzed by a chi-square test for quantitative variables and an independent t -test for qualitative variables. The comparison of all clinical parameters before and after treatment was performed by a paired t -test. The results after treatment showed that there was a significant improvement in all domains of OHIP-14 ( p = 0.001) except psychological disability ( p = 0.243). In addition, the OHRQoL of patients was significantly improved following the treatment.

Keywords: oral submucous fibrosis; oral health; oral potentially malignant disorders; oral cancer; quality of life (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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Citations: View citations in EconPapers (1)

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